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Bom-Benge ointment for external use 25g

Compound

Menthol or racemic menthol - 3.9%; methyl salicylate - 20.2%; medical petroleum jelly - 68.9%; petroleum paraffins - 7% or peppermint oil - 7.8%; methyl salicylate - 20.2%; medical petroleum jelly - 65.0%; petroleum paraffins - 7%

Indications for use

Bom-Benge is used externally for rubbing, as a distraction and analgesic for neuralgia, myalgia, arthralgia, etc.

Contraindications

Increased individual sensitivity to the components of the drug Bom-Benge. Dermatological diseases.

Directions for use and doses

Apply Bom-Benge ointment to painful areas of the body in a layer of approximately 1 mm, then rub into the skin. Depending on the intensity of the pain, repeat the procedure 2-3 times a day.

Storage conditions

In a place protected from light, at a temperature not exceeding 2-10°C.

Best before date

2 years.

special instructions

For external use only. Do not use with warming compresses. If skin irritation occurs, stop use. Avoid contact with eyes, mucous membranes, and areas of skin irritation. Do not use the drug for more than 10 days without consulting a doctor.

Description

White or yellow ointment with the smell of menthol and methyl salicylate

Conditions for dispensing from pharmacies

Over the counter

Dosage form

Ointment medicines

Manufacturer and organization accepting consumer complaints

SAMARAMEDPROM JSC

Action

When rubbed into the skin, the biologically active substances contained in Bom-Benge ointment cause irritation of the nerve endings, accompanied by a feeling of cold, slight burning and tingling, as a result of which they have a mild local anesthetic, distracting effect (menthol, peppermint oil), and also have anti-inflammatory effect (methyl salicylate).

Side effects

Allergic reactions to the components of Bom-Benge are possible.

Use during pregnancy and breastfeeding

When entering the systemic circulation, salicylates cross the placental barrier into the milk of nursing women and can adversely affect the fetus, especially in the third trimester of pregnancy (for example, cause premature closure of the ductus arteriosus or prolonged labor). Despite the fact that with topical use of methyl salicylates, their concentration in the blood plasma is not expected to increase to levels dangerous to the fetus, when deciding on the possibility of prescribing the drug during pregnancy and breastfeeding, the expected potential benefit of drug therapy and the possible risk to the fetus should be assessed

Interaction

Overdose

Overdose of menthol and methyl salicylate has been observed in isolated cases, mainly in children, due to accidental ingestion of drugs containing these substances. Symptoms of overdose: agitation, increased depth of breathing, hyperpyrexia, nausea, abdominal pain, vomiting and symptoms of central nervous system depression such as dizziness, unsteady gait, flushing, drowsiness, respiratory depression and coma. Treatment: symptomatic and supportive; correction of electrolyte and water balance, prescription of adsorbents and saline laxatives, forced diuresis, external cooling of the body; in severe cases - blood transfusion, hemodialysis. Overdose when applied topically occurs rarely and only when the drug is used incorrectly (application to mucous membranes, large areas of damaged or infected skin).

Bom-Benge ointment jars 25 g x1

MINISTRY OF HEALTH OF THE RUSSIAN FEDERATION

INSTRUCTIONS

ON THE MEDICAL USE OF THE MEDICINE

BOM-BENGE

Registration certificate number: LP-001685

Trade name , , Bom Benguet

International nonproprietary or group name, Menthol + Methyl salicylate

Dosage form , , , Ointment for external use

Compound:

Active ingredients: L-menthol – 3.9 g, methyl salicylate – 20.2 g.

Excipients: solid petroleum paraffins grades P-1, P-2 – 7 g, medical vaseline – up to 100 g.

Description: White to yellow ointment with the smell of menthol and methyl salicylate.

Pharmacotherapeutic group, Anti-inflammatory agent for topical use

ATX code: M02AC.

Pharmacological properties: Has analgesic and anti-inflammatory effects.

The local irritant effect of levomenthol helps reduce the intensity of pain. , , , , , , . , , , , a slight burning and tingling sensation followed by an analgesic effect.

Methyl salicylate is an anti-inflammatory pain reliever. Non-selectively inhibits cyclooxygenase, reducing the synthesis of prostaglandins. Normalizes increased capillary permeability, improves microcirculation processes, reduces swelling and infiltration of inflamed tissues.

Pharmacokinetics: When applied externally, the concentration of levomenthol in the systemic circulation is insignificant.

When applied externally, methyl salicylate penetrates into tissues through intact skin, while an analgesic concentration in the systemic circulation is not achieved. The effect is local only. Salicylates are excreted mainly by the kidneys; the rate of excretion depends on plasma concentration and urine pH.

Indications for use: Arthralgia, myalgia (muscle pain) before and after sports, pain in diseases of the periarticular tissues, lumboischialgia, radiculitis.

Contraindications: Hypersensitivity to any component of the drug, violation of the integrity of the skin and inflammatory skin diseases at the site of application, children under 12 years of age, pregnancy (III trimester).

With caution, Pregnancy (I-II trimester), breastfeeding period, children aged 12 to 18 years, salicylate intolerance, Reye's syndrome.

Use during pregnancy and breastfeeding

Before using Bom-Benge, if you are pregnant, or think you might be pregnant, or are planning a pregnancy, you should consult your doctor. During breastfeeding, you should consult your doctor before using Bom-Benge. When entering the systemic circulation, salicylates penetrate the placental barrier and into the milk of lactating women and can adversely affect

on the fetus, especially in the third trimester of pregnancy (for example, cause premature closure of the ductus arteriosus or prolonged labor) and the child. Despite the fact that with topical application of methyl salicylates

their concentration in the blood plasma is not expected to increase to a concentration dangerous for the fetus and child; when deciding on the possibility of using the drug during pregnancy and breastfeeding, the expected benefit of drug therapy for the mother and the possible risk for the fetus and child should be assessed.

Directions for use and doses

Externally. The required amount of ointment (2-4 g for adults and 1-3 g for children aged 12 to 18 years) is applied to the painful area and rubbed. If necessary, repeat the procedure after a few hours (up to 3 times

in a day). The duration of the course (without consulting a doctor) is up to 10 days. If after 10 days of treatment there is no improvement or the symptoms worsen or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, method of administration and in the doses indicated in the instructions.

Side effects , , The side effects listed below are given in accordance with the following gradations of the frequency of their occurrence: very often (≥ 1/10), often (≥ 1/100, < 1/10), infrequently (≥ 1/1000, <, 1/100), rare (≥ 1/10000, < 1/1000), very rare (< 1/10000) (including isolated reports), unknown frequency (it is not possible to determine the frequency of occurrence of side effects based on available data) .

From the immune system: in rare cases, hypersensitivity to the drug, shortness of breath in the context of hypersensitivity.

From the skin and subcutaneous tissues: hyperemia, itching, urticaria, skin rash, angioedema.

In patients sensitive to acetylsalicylic acid, skin allergic reactions, as well as angioedema, were observed when methyl salicylate was applied topically.

If you experience the side effects listed in the instructions or they get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Overdose. Overdose of levomenthol and methyl salicylate has been observed in isolated cases, mainly in children, due to accidental ingestion of drugs containing these substances.

Symptoms of an overdose of methyl salicylate: agitation, increased depth of breathing, hyperpyrexia.

Symptoms of an overdose of levomenthol: nausea, abdominal pain, vomiting and symptoms of central nervous system depression, such as dizziness, unsteady gait, flushing, drowsiness, respiratory depression and coma.

Overdose for external use occurs rarely and only with improper use of the drug (application to mucous membranes, large areas of damaged or infected skin).

Treatment: symptomatic and supportive, correction of water and electrolyte balance, administration of adsorbents and saline laxatives, forced diuresis, external body cooling, in severe cases - blood transfusion, hemodialysis.

Interaction with other drugs

The drug causes skin hyperemia and reflexively increases blood circulation in the subcutaneous tissue, thus, combined use with other local drugs can lead to increased absorption. The use of large quantities may increase the toxicity of methotrexate and reduce the therapeutic effect of hypoglycemic agents. Patients taking anticoagulants such as warfarin may experience bleeding because this drug contains salicylate. In patients sensitive to acetylsalicylic acid, skin allergic reactions, as well as angioedema, were observed when methyl salicylate was used externally. When combined with acetylsalicylic acid, toxic effects of salicylates may be observed. If you are using the above or other medications

(including over-the-counter medications) consult your doctor before using Bom-Benge.

Special instructions: For external use only.

Do not use with warming compresses or occlusive dressings.

If symptoms of skin irritation appear, discontinue use.

Avoid contact with eyes, mucous membranes, areas with impaired skin integrity and inflammation.

Do not use the drug for more than 10 days without consulting a doctor.

Cross-allergy to other salicylates is possible.

Impact on the ability to drive vehicles and machinery

Does not affect the ability to drive a car or operate machinery.

Release form: Ointment for external use.

25, 40 g in dark glass jars with a screw neck, sealed with gaskets and screw-on plastic lids.

25, 40 g in dark glass jars with a triangular rim with polymer stretchable lids.

25 g in aluminum tubes with polyethylene caps.

Each jar or tube with instructions for use is placed in a cardboard pack.

It is allowed to pack cans or tubes with an equal number of instructions for use in a group package.

Storage conditions: In a dry place at a temperature not exceeding 25 °C. , , Keep out of the reach of children.

Shelf life: 3 years. , , Do not use after the expiration date.

Dispensing conditions, , Without a prescription.

Manufacturer/Organization accepting claims: Tula Pharmaceutical Factory LLC

Russia, 300004, Tula, Torkhovsky proezd, 10, , Tel./fax