Pharmacological properties
Pharmacodynamics
Artron Complex is a combination drug with chondroprotective effectiveness. Its action is aimed at stimulating regenerative processes in cartilage tissue, as a result of which the mobility of articular surfaces improves, the range of motion in damaged joints increases, and pain in various diseases of the musculoskeletal system decreases.
The drug slows down the processes of degeneration in joint and bone tissue, stimulates the production and synthesis of intra-articular fluid, prevents the development and progression of osteoporosis, and has a positive effect on the tissue structure of the joint.
In patients receiving non-steroidal anti-inflammatory drugs, Arthron Complex slows down metabolic changes and damage to cartilage tissue.
The mechanism of action of the active substances is explained by their ability to stimulate the synthesis of type 2 collagen and proteoglycans. Glucosamine hydrochloride has an anti-inflammatory effect. Chondroitin sulfate normalizes the mineralization of the skeletal system and improves the course of recovery processes after bone fractures.
Pharmacokinetics
The maximum concentration of chondroitin sulfate after a single dose of 500 mg is observed after 3–4 hours in the blood, after 4–5 hours in the synovial fluid. Concentrations in blood plasma are lower than in synovial fluid. Bioavailability is 13–15%. Metabolites are eliminated primarily through the renal system within 24 hours after administration.
The bioavailability of glucosamine hydrochloride is 25–26%. The substance is well distributed in the tissues of the body, reaching the highest concentrations in cartilage tissue, the renal system and the liver.
Due to the metabolism of the drug, water, urea and carbon dioxide are formed. Approximately 30% of the dose taken persists for a long time in the connective tissue. It is excreted in its original form through the kidneys with urine, and partially through the intestines with feces.
Buy Glucosamine-chondroitin complex (GCC) Ultra capsules No. 90 in pharmacies
Glucosamine chondroitin complex Ultra Buy Glucosamine chondroitin complex Ultra in pharmacies MANUFACTURERS Pharmakor production (Russia)
GROUP of dietary supplements that support the functions of the musculoskeletal system
INTERNATIONAL NON-PROPENTED NAME no
Compound:
glucosamine sulfate chondroitin sulfate methylsulfonylmethane (MSM) boswellia extract
Action:
“GKH-Ultra” is a chondroprotective complex containing components that regulate metabolism in cartilage tissue and have an anti-inflammatory effect.
Recommended as an additional source of glucosamine sulfate and chondroitin sulfate. Methylsulfonylmethane (MSM) is an organic sulfur-containing compound, tasteless and odorless, which is a naturally occurring source of sulfur in a bioavailable form. MSM is the best source of active organic sulfur and significantly surpasses all other sulfur compounds in its positive properties. In the body, sulfur is necessary for the formation of muscles, ligaments, cartilage, connective tissue, nails, hair and skin. Sulfur is a necessary element for the synthesis of proteins involved in the construction of joints and ligaments. As people age, the concentration of sulfur in the body decreases, especially as a result of diet and metabolic disorders. Since sulfur plays an important role in human life, it must be present in the diet. MSM, as a source of sulfur in a bioavailable form, is used for problems with joints, as well as for unsatisfactory condition of the skin, hair and nails.
Glucosamine is involved in the biosynthesis of hyaluronic acid and proteoglycans necessary for the formation of articular cartilage and collagen synthesis, and promotes normal calcium deposition in bone tissue.
Chondroitin is a high molecular weight polysaccharide that is found in significant quantities in connective tissue, especially cartilage. Due to its viscosity and chemical structure, chondroitin prevents compression of connective tissue and plays the role of a kind of lubricant of articular surfaces.
Boswellia extract contains boswellic acids, which have a significant anti-inflammatory effect, help reduce pain, and improve the mobility of joints and the spine.
Recommendations for use:
adults: 1 capsule 3 times a day with meals. Duration of treatment: 1 month. If necessary, the reception can be repeated.
Contraindications:
individual intolerance to product components, pregnancy and breastfeeding. Before use, you should consult your doctor.
Release form:
60 or 90 capsules in a polymer jar.
Storage conditions:
store in a dry place, protected from light, out of reach of children at a temperature not exceeding +25°C.
Best before date:
2 years. Not a medicine. For whom is the GHC-Ultra complex in capsules recommended?
For adults over 18 years of age who:
Mainly lead a sedentary and sedentary lifestyle Have problems with the musculoskeletal system Experience physical stress on ligaments and joints Play various sports
Indications for use
- Osteochondrosis, osteoarthrosis, spondyloarthrosis and other diseases of joints and bones of a degenerative nature;
- Osteopathy, chondropathy, periodontopathy;
- Elimination of severe pain in older people and athletes with joint damage;
- Restoration of cartilage tissue;
- Conditions after operations on the musculoskeletal system and after bone fractures.
Thanks to the glucosamine included in its composition, Artron Complex helps restore the surface of cartilage and stimulates the process of aminoglycan synthesis. Glucosamine enhances the effect of chondroitin sulfate, aimed at normalizing the production of intra-articular fluid, reducing pain in the joints, and improving their mobility.
ArtraSil Super/MSM complex glucosamine with chondroitin 1200 mg No. 90 tab. in Izhevsk
Application area
- Contains three active substances: chondroitin sulfate, glucosamine hydrochloride and methylsulfonylmethane. The product is enhanced with methylsulfonylmethane (a substance based on organic sulfur), helps improve the effect of anti-inflammatory drugs, and prevents the destruction of joints.
- To protect joints from destruction. Improves mobility. Enhanced with MSM, provides anti-inflammatory effect.
- One package is enough for a minimum course of use.
- Manufactured in compliance with the international quality standard - ISO 9001P.
Recommended as a dietary supplement, a source of glucosamine and chondroitin sulfate containing methylsulfonylmethane.
Content of biologically active substances (BAS) in 1 tablet: glucosamine 280 mg, chondroitin sulfate 270 mg, methylsulfonylmethane 200 mg. Glucosamine
- a substance produced by the cartilage tissue of joints. Its lack in the body is one of the factors in the development of diseases of the musculoskeletal system. Glucosamine helps restore articular cartilage, normalize the production of intra-articular fluid, improve joint mobility, nourishes and restores chondrocytes (the main cells of cartilage tissue).
Chondroitin sulfate
is a high molecular weight polysaccharide that belongs to the group of proteoglycans. It is a specific component of cartilage, i.e. Found exclusively in cartilage tissue, it gives the joint elasticity and shock-absorbing properties by retaining water in the tissue. Chondroitin sulfate helps increase the strength of the connective tissue of the ligamentous apparatus. It is part of the synovial fluid, which ensures gliding of articular surfaces and softens joint friction.
MSM (methylsulfonylmethane)
is a natural compound that is a bioavailable form of sulfur, which is found in some amount in the human body.
Sulfur
- an important structural element of glycosaminoglycans. MSM promotes better absorption of glucosamine and chondroitin by the body, thereby ensuring flexibility and elasticity of connective tissue, is necessary for the biosynthesis of collagen - a protein of cartilage tissue, maintains the flexibility and permeability of cell membranes, promoting effective metabolism. MSM affects the capacity of cells, increasing their permeability and elasticity, which helps to better cleanse the body of toxins and allergens.
Not a medicine.
Side effects
- from the gastrointestinal tract: dyspepsia, nausea/vomiting, stomach pain, diarrhea, constipation, flatulence;
- from the nervous system: dizziness, headache, insomnia, drowsiness, general weakness, increased fatigue;
- from the immune system: hypersensitivity reactions, including skin rash, urticaria, erythema, itching, dermatitis, maculopapular rash, edema (including angioedema);
- other reactions: visual disturbances, hair loss, general weakness, swelling.
Note!
The description of the drug Artron on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use. Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug).
Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
special instructions
The recommended dosage should not be exceeded.
One of the components of Artron Complex - glucosamine - is extracted from shellfish shells, and therefore patients with allergies to shellfish should take this drug with caution.
Impact on the ability to drive vehicles and complex mechanisms
No special studies have been conducted on the effect of Artron Complex on the ability to drive vehicles or other potentially dangerous mechanisms. But when performing types of work that require concentration and quick reactions, it is necessary to take into account possible side effects such as drowsiness, dizziness, and visual disturbances.
Composition and release form
Composition: 1 film-coated tablet of the drug Artron Complex contains:
- Chondroitin sulfate – 500 mg;
- Glucosamine hydrochloride – 500 mg;
- Excipients.
Release form:
Film-coated tablets, 10 pieces in a blister pack, 1 blister pack in a cardboard box.
Film-coated tablets, 30, 60 or 120 pieces in a bottle made of polymer materials, 1 bottle in a cardboard package.
Reviews about Artron Complex
According to reviews, Artron Complex reduces the severity of pain and increases the range of motion in damaged joints, is well tolerated and does not cause side effects. However, patients note that long-term treatment is required to obtain the necessary therapeutic effect. To achieve better results, simultaneous physiotherapeutic procedures and physical therapy are recommended.
The disadvantages of many include the high cost, especially considering that the minimum recommended course of treatment is 3 months.
Pharmaceutical action
a combined chondroprotective drug that stimulates the regeneration of cartilage tissue. Glucosamine and sodium chondroitin sulfate take part in the biosynthesis of connective tissue, prevent cartilage destruction and stimulate tissue regeneration.
Chondroitin sulfate is a high molecular weight mucopolysaccharide that takes part in the construction of the basic substance of cartilage and bone tissue. Improves phosphorus-calcium metabolism in cartilage tissue, inhibits enzymes that disrupt the structure and function of joint cartilage, and inhibits the processes of degeneration of cartilage tissue. Stimulates the synthesis of glycosaminoglycans, normalizes the exchange of hyaline tissue, promotes the regeneration of the surface of cartilage and joint capsule. Prevents compression of connective tissue, increases the production of intra-articular fluid, improves the mobility of affected joints. Slows down resorption and accelerates bone tissue repair processes, reduces calcium loss, and inhibits the progression of osteoarthritis. It has analgesic properties, reduces the severity of joint pain, pain at rest and when walking, and manifestations of inflammation.
Glucosamine stimulates the biosynthesis of aminoglycans, helps restore cartilage surfaces and reduce degenerative changes in joints. Normalizes the production of intra-articular fluid, reduces the severity of pain in the joints, improves their mobility.