With age, the synthesis of natural hyaluron in the body decreases, which leads to discomfort in the joints, pain, and limited mobility. Hyaluronic acid, produced in older people, has a low molecular weight, so its concentration in cartilage is not enough for its normal functioning.
To compensate for the deficiency of natural synovial fluid, traumatologists and orthopedists recommend intra-articular injections of liquid prostheses based on sodium hyaluronate, as well as their synthetic analogues. After each course, the motor activity of the joint improves, the structure of the cartilage and its internal structure are restored. The only “but” is that the effect is temporary, and its duration depends on the medication. What is the difference between the liquid dentures that are most commonly used today?
Not all liquid synovial fluid grafts are equally effective
Indications for use
Extracts from medicinal plants are easily absorbed in the intestines, after which the therapeutic effect immediately begins.
Several pathologies are stated among the indications:
- elevated cholesterol levels;
- diseases of joint tissues;
- rheumatism and muscle pain;
- seizure activity;
- stressful situations;
- swelling of the arms and legs.
Additionally, the drug prevents salt deposition and stimulates the restoration of cartilage tissue.
Compound
Montalin is a medicine for joints, each dose of which contains:
- centella asiatica – 35%;
- Gloriosa luxurious – 25%;
- mimosa bashful – 15%;
- phyllanthus urinaria – 10%;
- field sow thistle – 10%;
The components also include other herbs added in amounts up to 100% of the weight of each capsule.
- Centella asiatica is a plant with many healing qualities. It is a creeping shoot from the umbrella family. Another famous name is Gotu Kola. The leaves contain various essential oils and bioflavonoids, asiatic, madasiatic, centillic, centoylic acids and vitamins. Centella asiatica extract effectively relieves swelling through a mild diuretic effect.
The plant stimulates the removal of toxins from the body, supports liver function, helps reduce appetite and normalizes digestive processes. Due to its rich composition, centella asiatica is classified as a highly allergenic agent.
- Gloriosa luxurious - a climbing plant from the Liliaceae family. The length of the vine can reach 2 m. In tropical regions of Africa and Australia it is considered a weed, widespread everywhere. Gloriosa extract prevents excessive cell division and helps eliminate the symptoms of gout. Has poisonous properties. Just 6 mg of the alkaloid colchicine, contained in all parts of the plant, can cause death in humans. Therefore, use in medicinal products is strictly standardized.
- Mimosa pudica - the plant stimulates regeneration, due to which the renewal of inflamed tissues in the joints is significantly accelerated.
The extract has several beneficial effects:
- blocks the development of infections when injured;
- used as an antidote for snake bites;
- lowers body temperature and relieves toothache;
- promotes recovery from dysentery;
- stops severe bleeding.
Mimosa also has an effect on digestion, cardiovascular system, endocrine and nervous systems, and helps cleanse and renew blood throughout the body.
- Phyllanthus urinaria - its extract has powerful hepatoprotective properties, recommended for reducing cholesterol levels in the blood, preventing the formation of cholesterol plaques on the walls of blood vessels, the development of urolithiasis and diabetes. Phyllanthus has pronounced activity against the hepatitis B virus and is widely used among adherents of Ayurvedic medicine. Regular use also helps prevent the development of liver cirrhosis of any etiology.
- Field sow thistle - its leaves contain a large amount of ascorbic acid, fatty oils, carotene, choline and other useful substances and vitamins. Thanks to a rich set of various biologically active substances, sow thistle has a beneficial effect on the body in case of neuroses, nephritis and joint pathologies, in particular. Its roots contain a lot of inulin, a natural prebiotic, which also helps to normalize the intestinal microflora.
How does it work?
"Montalin" has a positive effect on the entire body as a whole, improving the functioning of the following systems:
- Musculoskeletal. Wounds on the skin heal, connective tissues are strengthened, pain and stiffness during movements are eliminated.
- Nervous. Mental activity and stress resistance increases, tension is relieved.
- Cardiovascular. The walls of blood vessels are strengthened and the blood is purified.
- Digestive. The metabolic process is accelerated, complete absorption of fats and carbohydrates is ensured, and microflora is normalized.
- Uric. The work of the liver and gall bladder is stimulated.
- Immune. The body's resistance to infections increases and energy reserves are replenished.
In what form is it produced?
The drug is available in cardboard packages. Each box contains 10 bags of 4 capsules. Their contents are a homogeneous dark powder. The cost of 1 package is around 800-1200 rubles. The drug is distributed through online pharmacies. Delivery conditions also differ.
The bags are made from thick foil, which prevents contact of the powder with the external environment. But exposure to elevated temperatures is undesirable. When stored in a cool and dark place, the medicinal product fully retains its properties throughout its shelf life.
Brief description of the drug
An effective medicine for inflammation of the joints of the legs is Montalin. These are capsules containing natural components of plant origin that are effective in combating various pathologies of the musculoskeletal system. To restore joints to their previous mobility and relieve debilitating pain, Montalin should be used after consultation with a doctor, who will assess the need for such treatment and prescribe effective dosages.
Release form and packaging
The medicine is a light brown powder, hermetically packaged in capsules . The gelatinous shell has a brown tint. One package contains 40 capsules. The drug is available in cardboard packages. Each box contains 10 bags of 4 capsules.
Compound
All components of the medicine are natural ingredients that were carefully selected during the development process. They act gently, but greatly enhance each other's impact. The medicine contains extracts and extracts of the following plants:
- Centella asiatica. It has anti-inflammatory properties and can activate metabolic processes. It is also used as an antiseptic. Harmonizes the functioning of the urinary system of men and women, thereby eliminating swelling in the area of inflammation. Improves blood flow to pathological lesions, favors regenerative mechanisms. It also activates the synthesis of collagen fibers in articular joints. Used in the pharmaceutical industry as a natural tumor inhibitor.
- Gloriosa is luxurious. The root of the plant has analgesic, antitumor and antiseptic properties. Included in a number of drugs for the treatment of joints and gout. A very active component that is used in preparations exclusively in small doses.
- Field sow thistle. Dried juice affects connective tissue, forcing it to recover in areas of damage. It also has a rejuvenating, tonic effect and relieves the inflammatory process.
- Mimosa is bashful. Contains tannin and alkaloids that remove swelling due to diuretic properties. Reduce the intensity of inflammation and initiate wound healing.
- Phyllanthus niruri. Flavonoids, alkaloids, lignans and tannins of this plant are aimed at activating the functioning of the organs of the excretory system. This leads to the elimination of toxins at the cellular level. Kidney stone formation is reduced.
- Pelargonium (scented geranium). Organic acids and flavonoids act as antiseptics, regenerating and anti-inflammatory agents.
Natural raw materials are safe because they do not contain synthetic ingredients. This leads to minimization of side effects and contraindications.
Packaging of the drug Montalin
Manufacturer
The manufacturer is the PJ concern. AIR MADU MAGELANG, produced in Indonesia in Magelang.
Application
For maximum therapeutic effect, it is recommended to drink the capsules 2 hours before or after meals along with plenty of cool water.
For children under 18 years old
The drug can be taken by minor children. However, in this case, it is imperative to discuss this possibility with the treating or observing specialist.
Additionally, you need to take into account the risk of developing allergies, especially for those teenagers who are highly reactive to natural extracts, herbs and herbal preparations.
For adults
The course of treatment depends on the type of disease, its form and the severity of the symptoms present. The total number of packages can reach 10 pieces.
It is recommended to repeat individual courses after a 1-month break, for each of which only 1 box of 40 capsules is provided. 1 course of therapy should not exceed 20 days of taking capsules twice a day.
For pregnant
Montalin is a medicine for joints containing highly active components. Their effect during pregnancy in terms of the effect on the fetal organs has not been sufficiently studied, so women should not take such drugs at this time.
If necessary and if symptoms are difficult to tolerate, therapy with local corticosteroids or injections of synovial fluid is possible.
For the elderly
For older people, the drug can be taken by analogy with adults. If there are existing disorders of the liver or kidneys, this issue should be resolved by the local physician.
Pharmacokinetics
Montalin is a medicine for joints, the main volume of which is absorbed in the upper parts of the small intestine. The speed of onset of the therapeutic effect will depend on the time of evacuation of the contents from the stomach to this area.
The speed and completeness of absorption is greatly influenced by the intensity of peristalsis and the type of accompanying food. During treatment, it is advisable to limit the consumption of excessively hard foods and excess fiber.
After oral administration, the capsule dissolves quickly. Under the influence of digestive juices, herbal extracts break down into simpler elements, after which these particles easily penetrate through the intestinal walls into the circulatory and lymphatic system.
The ingredients have a complex therapeutic effect, so it is not possible to identify specific distribution routes and areas of special activity.
Contraindications
Particular caution when starting to take any medications with natural ingredients should be exercised by those people who have a history of allergic reactions and other symptoms of intolerance.
Other contraindications:
- impaired renal or liver function;
- diabetes mellitus type I or II;
- ulcerative lesions of the stomach;
- childhood;
- pregnancy.
If there are any contraindications, the appropriate method of therapy should be determined exclusively with the observing specialist.
Overdose
In case of overdose, effects similar to side effects may occur, but their severity will be especially pronounced. First of all, you should call an ambulance.
Recommendations at home before her arrival:
- Gastric lavage. The victim must drink water repeatedly and then induce vomiting. The method is suitable if no more than 30 minutes have passed after taking the capsules.
- Use of enterosorbents. Drugs such as Enterosgel, Polysorb, Polyphepan will help neutralize drug residues.
- Taking laxatives – Fortrans, Microlax and others.
- Cooling your head with an ice pack will slow the blood flow and prevent toxin damage.
- Drinking plenty of fluids will restore fluid loss; weak tea or mineral waters are good options.
After this, you need to place the victim under a warm blanket and wait for the arrival of emergency medical services.
Side effects
If the dosage and frequency of administration are observed during the standard treatment period, the risk of unwanted effects is minimal.
But in some cases the following side effects are possible:
- drop in blood pressure;
- allergic reactions;
- swelling of tissues.
If their severity becomes strong enough, it is recommended to interrupt treatment and seek medical help. In some cases, treatment can be continued when combined with symptomatic therapy.
Drug interactions
Montalin is a medicine for joints with a rich content of various biologically active substances. Therefore, combination with traditional medicine can lead to increased activity and provoke an increase in the toxicity of both drugs.
Patients taking potassium-based drugs or potassium-sparing drugs should not use Montalin, as simultaneous use increases the risk of developing hyperkalemia. Simultaneous use with anticoagulants is also prohibited in order to prevent possible problems with blood clotting.
Analogs
The drug is not registered in the register of medical products for the treatment of joint diseases, therefore it has no complete analogues. In addition to it, the pharmaceutical market offers a large number of other effective medicines, tablets and capsules.
Diclofenac
The substance quickly and permanently blocks joint pain and helps relieve inflammation.
Produced in several dosage forms:
- injection;
- tablets and capsules;
- rectal suppositories;
- ointments and gels.
Diclofenac indiscriminately inhibits the enzymes COX-1 and COX-2, thereby disrupting the metabolism of arachidonic acid and the production of prostaglandins responsible for the development of the inflammatory process.
When applied externally, no more than 6% of the dose is absorbed; a single dosage for intramuscular administration should not exceed 75 mg. The frequency of administration is no more than 1 time per day. The duration of therapy should also be strictly limited in accordance with the recommendations of the instructions for use of the specific dosage form.
Meloxicam
A drug from the NSAID group containing meloxicam is available in different dosage forms.
There are 2 types of dosage:
- 7.5 mg;
- 15 mg.
Meloxicam belongs to the oxicam class of NSAIDs, derivatives of enolic acid. The drug has antipyretic, anti-inflammatory and analgesic effects. The standard course of treatment does not exceed 3-6 days. Longer therapy is accompanied by selectivity for COX-2, its activity decreases.
Meloxicam has a lesser effect of this kind on the activity of COX-1, which is responsible for the synthesis of prostaglandins, which are involved in protecting the mucous membranes of the gastrointestinal tract. Thanks to this, the drug less often leads to the development of erosive and ulcerative lesions of the gastrointestinal tract.
Other side effects are recorded in approximately 1 case out of 100. Caution during treatment should be exercised by patients who have had an acute form of gastric or duodenal ulcer in the past and are constantly taking anticoagulant drugs.
Don
The drug belongs to the correctors of tissue metabolism in bones and cartilage.
Release forms:
- solution for intramuscular administration – 2 ml ampoules, 6 pcs. in combination with a solvent;
- powder for preparing the solution - bags of 1.5 g, 20 and 30 pcs.;
- film-coated tablets – PET bottles of 60 and 180 pcs.
Active substance – glucosamine:
in tablets | 0.75 g per 1 piece. |
in powder | 1.5 g in 1 package |
in solution | 0.4 g in 1 ampoule |
The drug effectively blocks inflammation, compensates for the internal deficiency of glucosamine, and enhances the production of proteoglycans and sodium hyaluronate in the synovial septum.
After injection into the muscle, the bioavailability of the solution reaches 95%. The drug is quickly distributed in the tissues of the body, the half-life is about 60 hours. Basically, the substance is excreted by the kidneys. The drug administration regimen is 3 times a week for 1.5 months. If necessary, the duration can be increased after consultation with the doctor.
Special instructions - due to the lidocaine contained in the solution, Dona injections are contraindicated for the treatment of patients with conduction pathologies in the heart and acute insufficiency of its functions, chronic epilepsy, during gestation and subsequent breastfeeding, as well as for children under the age of 12 years old.
Drugs for synovial fluid replacement
The pharmaceutical market offers a fairly large number of special solutions for replacing synovial fluid - a thick elastic mass that fills the internal cavity of the joints. In the body, it acts as a kind of lubricant, thereby preventing abrasion of the articular surfaces and increasing the range of movements.
It consists of 2 components:
- liquid;
- protein-saccharide.
The last element is sodium hyaluronate, a polysaccharide from a type of glycosaminoglycan. It ensures stabilization of the joint structure itself, forming complex molecules with high molecular weight.
Thanks to this action, synovial fluid prostheses provide high elasticity of cartilaginous tissue, and joints glide virtually without friction even under significant physical exertion.
The administration of the drug does not cause any negative reactions in the body. The treatment regimen, as a rule, involves a single administration of the solution per week for 1.5 months. Synovial fluid grafts are supplied in sterile syringes, ready for use.
Montalin can be used not only to treat joints, but also to prevent the development of pathologies. In this case, natural medicines make it possible to prolong the functionality of tissues with particular safety without the use of strong medications.
Article design: Vladimir the Great