Lytic mixture for fever for adults, injections, tablets

The human body is capable of withstanding enormous loads, but at the same time it can fail by catching ARVI. Many diseases are accompanied by elevated body temperature, which is how the body copes with infection. The temperature should not be artificially lowered to certain numbers, however, if the mercury column shows 39 degrees or higher, urgent measures must be taken. If the usual antipyretic drugs do not cope, then a lytic mixture is used; the dosage for adults should be calculated very carefully.

How to lower an adult's fever: 8 best drugs

September 14, 2021
24217

4.6

1

Content

• How to choose fever pills
• Why does the temperature rise
• What to do at elevated temperatures
• How to reduce fever without medication
• The best antipyretics
• Paracetamol
• Nimesil
• Nurofen Long
• Theraflu ExtraTab
• Ibuklin
• Maxicold
• Rinza
• Aspirin

An increase in temperature is a signal from the body that there is an inflammatory process somewhere. An increase in temperature is a protective response of the immune system, the purpose of which is to eliminate the problem. But there are situations when the temperature urgently needs to be brought down. We will tell you which antipyretic pills are best to choose.

What are the side effects of the lytic mixture?

Uncontrolled treatment with this drug can be disastrous for both children and adults. You should always strictly follow your doctor's instructions and not use the mixture too often. The body of a person who constantly fights hyperthermia in this way may become resistant to other medications. Quite often the drug is easily tolerated, but drowsiness and distraction are possible.

How to choose fever pills

Antipyretic drugs come in two categories:

• antipyretics
  (such drugs have a good antipyretic effect, they relieve pain a little, but do not in any way affect the source of inflammation). These are mainly paracetamol-based drugs;
• NSAIDs
  (these drugs relieve inflammation, reduce pain and reduce fever). In this category, the most famous drug is aspirin, but it has a lot of side effects. Today, instead of aspirin, there are many other, safer drugs for fever. One of them is ibuprofen.

Mixture composition

Data on what is included in the classic recipe for a lytic mixture for adults can be seen in the following table:

Analgin quickly soothes pain and relieves fever. No-spa or papaverine eliminates spasms and has a hypotensive effect on the body. They dilate blood vessels and increase heat transfer from the body. The sedative drug diphenhydramine increases the effectiveness of analgin and also relieves allergic manifestations. This medication also improves breathing and eliminates runny nose.

Lytic mixture depending on temperature

Instead of diphenhydramine, you can use:

• tavegil;
• diazolin;
• suprastin.

The lytic mixture for fever helps adults if a febrile state is accompanied by dehydration and convulsions. A similar drug helps out faster than conventional pharmaceutical drugs. It instantly relieves fever and relieves pain. But do not forget that such therapy may be accompanied by allergic reactions.

The main and most effective medication in the urgent antipyretic compound is analgin. There should be exactly half of it in the product. Analgin relieves fever and reduces temperature. Diphenhydramine 1% with a strong sedative effect is mainly replaced with suprastin or tavegil. Papaverine, like the previous medication, increases the effect of analgin and has antispasmodic properties.

Why does the temperature rise

The temperature can rise for various reasons. All of them can be divided into the following groups:

1. Infectious diseases caused by viruses (ARVI, influenza, intestinal infections, coronavirus, etc.).
2. Infections caused by bacteria (tonsillitis, bronchitis, pharyngitis, pneumonia, skin inflammation and intestinal infections).
3. Complications after operations, post-traumatic complications due to infection and tissue inflammation.
4. Autoimmune diseases.
5. Oncological processes (including blood diseases).

Also, body temperature may increase after overheating, against the background of endocrine diseases, due to problems with metabolism or taking certain medications. Non-pathological causes of fever also include: stress, premenstrual syndrome, menstruation, pregnancy, teething in babies.

By the way, a slightly elevated temperature can sometimes be a variant of the norm - as an individual feature of the body.

Why measure temperature?

The measurement has primarily diagnostic value. We approach conditions in which the temperature is above or below the conventional limit of 38 degrees Celsius a little differently. Since most fevers in our latitudes go away on their own within 3 days, in the absence of threatening symptoms, I recommend observation for 72 hours after the first rise in temperature above 38. If after this period it rises again above 38, a doctor’s examination is necessary to decide whether whether this is a lingering virus (and we continue to observe) or whether more aggressive intervention is required. Thus, we measure temperature to determine treatment tactics, but not to resolve the issue of antipyretic treatment.

What to do at elevated temperatures

If you have a slight fever, do not rush to immediately swallow an antipyretic. If the numbers are 38-38.5, just try to have a good rest, drink a lot of warm liquids and get some sleep. Give the body the opportunity to cope with the infection on its own.

If you feel normal at an elevated temperature (up to 38.5 degrees), you are at home, you can try to lower the temperature without pills: wipe your body with a damp towel moistened with water at room temperature.

But if you do not tolerate an increase in temperature, it has risen above 38.5 degrees, be sure to take an antipyretic. Especially if you have a headache, general weakness or convulsions (in this case you need to call an ambulance).

Take any medications (including antipyretics) with caution if you are prone to allergies. Often tablets or syrups for fever contain flavorings and dyes.

Often the dose of fever medication is calculated based on body weight. If a child’s temperature has risen, it can only be brought down with certain medications, so be sure to check the instructions for contraindications.

Tablets for fever, as we wrote above, are divided into two groups: NSAIDs and antipyretics. Drugs based on NSAIDs in combination with antispasmodics are good at reducing fever, which does not decrease for a long time (usually emergency doctors give such injections). But before using drugs with NSAIDs, it is necessary to assess the general health of the patient - NSAIDs are contraindicated for gastrointestinal diseases.

At elevated temperatures, it is imperative to look for the cause and fight it. This is usually a viral or bacterial infection. If it is bacterial, antibiotics are prescribed, but if it is a virus, then there is no special treatment, only symptomatic. Antiviral drugs are ineffective here. It is important to immediately consult a doctor if antipyretic drugs do not reduce the temperature well or the condition only worsens.

What is better - injecting or drinking?

Only the treating specialist has the right to decide which form of the lytic mixture is better. In terms of effectiveness, tablets and injections are almost the same. Both forms of the drug are similar to each other in their effects on internal organs. Therefore, both injections and tablets are suitable for reducing high fever.

When administered intramuscularly, the lytic mixture begins to show its effect within 10 minutes. The tablets used to formulate such an emergency remedy act only after 30-60 minutes.

If the temperature is critically high (more than 39°), then it is better to give injections with a lytic mixture. Instead of tablets, sometimes patients with high fever are given the contents of ampoules used for injections to drink. But if they are used in this way, an overdose and harm to the body can occur, since analgin in concentrated form is very strong.

Before using the lytic mixture, an allergy test must be performed with it. To do this, the prepared solution in an amount of 1-2 drops is carefully injected behind the patient’s lower eyelid. If after a few minutes no reaction is detected (for example, irritation or itching), this will mean that there is no allergy to the lytic agent.

If the test is positive, instead of an urgent antipyretic, other methods of getting rid of high fever are used:

• Vodka rubbing, which, however, leads to the following side effects:
• mild sweating;
• slow blood circulation;
• vascular spasm.
• Vinegar rubdown, along with which, in case of complications, you will also have to take medications that relieve vascular spasm.
• Cool compresses on forehead and wrists.

A fast-acting antipyretic drug consisting of 3 components is allowed for administration not only in the absence of an allergy to it, but also in cases where it does not help to get rid of the elevated temperature:

• ibuprofen;
• paracetamol;
• aspirin;
• naklofen;
• non-steroidal anti-inflammatory drugs;
• indomethacin

The lytic mixture must be used to relieve severe fever in:

• elderly;
• young children;
• patients with cardiovascular problems.

An urgent antipyretic agent in ampoules or tablets helps to avoid:

• convulsive syndrome;
• disturbances of cardiac activity and electrolyte balance;
• phenomena of intravascular coagulation.

Conventional medications for fever are not always effective. A multicomponent lytic mixture helps to quickly reduce fever in adults. Medical professionals also call it the “troika.” Such an active drug consisting of several components is completely harmless and effective.

How to reduce fever without medication

There are non-drug methods of reducing fever that can be used either alone or while taking antipyretics.

1. If you are feeling chilly, you should not wrap yourself up too much, so as not to disrupt heat transfer - this will only aggravate the condition. You need to cover yourself until you are comfortable, but not too hot.
2. Don't forget to have enough liquid. The body tries to cool down - the body sweats and loses fluid. If there is little water in the body, the condition will worsen. The liquid also helps remove waste products of pathogenic microorganisms from the body.
3. If you don't have an appetite, don't force yourself (or your child) to eat. During illness, all the body's strength is spent fighting infection.
4. To reduce your temperature without medication, wipe your body with a towel moistened with water at room temperature.
5. At elevated temperatures, ice can be applied to large vessels. First you need to crush the ice and put it in a bag. An ice pack should be applied through a towel - to the groin folds, armpits, forehead, popliteal fossa.
6. Raspberry, cherry, currant, and strawberry jam are considered folk remedies for fever (you can add tea or simply stir with warm water).

If the above methods of reducing fever do not work, be sure to take an antipyretic.

What temperature should be lowered in a child with influenza and ARVI?

High temperature forces the child's body to turn on its protective function. In this case, there may be a general deterioration in the form of malaise and headaches. The child becomes lethargic and whiny, which brings a lot of anxiety to parents. Before bringing down a child’s high temperature, you need to clarify significant nuances.

A slight increase in temperature does not lead to serious consequences and does not require any measures to be taken. Parents need to have reliable information about what temperature should be lowered. Improper actions can cause weakened immunity. There is a risk of developing possible complications and the disease may become protracted.

Cases when you need to bring down the temperature in children:

• 37.2-37.9°C (low-grade fever) – should be taken for newborns up to 2 months of age if indicated;
• 38.0-38.9°C (febrile) – antipyretics must be given in all cases;
• over 41.0°C (hyperthermic) - you need to call an ambulance if the drugs do not lower the readings on the thermometer.

It is necessary to call an ambulance if febrile spasms appear - this is intolerance to high temperature, an individual feature of the child’s body. This condition usually does not occur in children over 6 years of age (provided there are no pathologies in the central nervous system).

Chronic or acute diseases in cardiology, neurology or lung disease require lowering the temperature in children if the readings are above 38°C. Otherwise, complications from the heart, nervous system and respiratory organs cannot be ruled out.

If you have difficulty lowering your temperature, you should immediately seek medical help. If the thermometer has barely reached 37°C, and the child looks lethargic and his health is only getting worse, you should not expect a further increase in the readings on the thermometer.

Paracetamol

You can buy Paracetamol in tablets, capsules, syrup, suspension and in the form of rectal suppositories. The active substance is paracetamol. The antipyretic is available without a prescription. This is the safest remedy, effective and prescribed for ARVI. Compared to other drugs, Paracetamol is weaker because it does not have an anti-inflammatory effect - for bacterial infections it is better to choose other tablets for fever. Paracetamol moderately reduces headaches and reduces general malaise. The temperature begins to drop 30-40 minutes after taking the drug, the effect lasts for 4-6 hours. Paracetamol is safe for both children and the elderly, pregnant and lactating women. The only exception is people with severe liver disease and chronic alcoholism. Paracetamol should not be taken with alcohol, for prophylaxis or as a course - only at high temperatures.

Paracetamol MS

Medisorb, Russia

Paracetamol is used for: relieving moderate or mild pain (headache, toothache, migraine, sore throat, neuralgia, myalgia);
reducing elevated body temperature during colds and other infectious and inflammatory diseases. Paracetamol is intended for symptomatic therapy, reducing pain and inflammation at the time of use, does not affect the progression of the disease. from 2

5.0 1 review

271

• Like
• Write a review

Dosage and method of administration for adults

A potent lytic mixture for adults is almost harmless. It includes three drugs, thoroughly mixed together.

In ampoules

When preparing a quick-acting mixture for high fever for adults, they are guided by the rules for preparing doses from the following components:

• 2 ml of 50% analgin;
• 1 ml of 1% diphenhydramine;
• 2 ml of 2% no-shpa.

The above dosage can be used by people weighing up to 60 kg. For those who weigh heavier, it is recommended to add another 1/10 of this product for every 10 kg of their own weight.

The lytic mixture for fever in adults can have both intramuscular and oral forms. If an allergy occurs, the stomach should be rinsed.

In tablets

Tablet administration, unlike injection, leads to results only after half an hour. Analgin also irritates the stomach and leads to unpleasant phenomena.

If the lytic mixture cannot be consumed in ampoules, then it is used in tablets:

• 1 PC. Baralgina or Analgina;
• 1 PC. Suprastin or Diphenhydramine;
• 1 PC. Papaverina or No-shpa.

Nimesil

The active ingredient of the antipyretic drug is nimesulide. These are NSAIDs with pronounced anti-inflammatory, antipyretic and analgesic effects. You can buy Nimesil at the pharmacy in individual sachets. Among the contraindications to taking Nimesil are diseases of the gastrointestinal tract (the full list is listed in the instructions, so be sure to read it before taking the drug). "Nimesil" should be used only after consultation with a doctor.

Nimesil

Berlin-Chemie/Menarini, Germany

Treatment of acute pain (back pain, lower back pain; pain syndrome in the musculoskeletal system, including injuries, sprains and dislocations of joints, tendonitis, bursitis; toothache);
— symptomatic treatment of osteoarthritis with pain syndrome; - algodismenorrhea. The drug is intended for symptomatic therapy, reducing pain and inflammation at the time of use. from 24

5.0 2 reviews

1777

• Like
• Write a review

Nurofen Long

"Nurofen Long" for fever is sold in tablets, capsules, syrup. You can also buy a combination drug "Nurofen" with paracetamol. Nurofen does not require a prescription, and its active substance is ibuprofen (NSAID). Nurofen Long perfectly reduces the temperature literally 20 minutes after taking the tablet, and the effect lasts for 8 hours. The drug also reduces muscle pain, relieves headaches and inflammation, relieves nasal congestion, and relieves pain. Nurofen Long is recommended for bacterial infections and exacerbation of chronic diseases. The drug helps with elevated temperature due to ARVI. Contraindications include intolerance to ibuprofen and fructose, gastrointestinal diseases (including gastritis and ulcers), liver and kidney diseases. You should not drink alcohol while taking Nurofen. Nurofen is prescribed during pregnancy only if there is an urgent need.

Nurofen Long

Reckitt Benckiser, Netherlands

Backache;
joint pain; muscle and rheumatic pain; neuralgia; headache; migraine; toothache; painful menstruation; a sore throat; feverish condition; cold and flu symptoms. The drug is especially indicated for the symptomatic treatment of pain requiring a more pronounced analgesic effect than ibuprofen or paracetamol alone. from 137

579

• Like
• Write a review

Syringe

Three-part syringes are often used. Sometimes during injection you need to make an effort to move the syringe plunger. This will result in jerks that cause pain. The syringe must have a rubber seal that is mounted on the piston. This is necessary for its smooth movement, without shocks and painlessly.

A syringe for analgin injection should be selected based on simple rules:

1. It must be in an individual plastic cassette.
2. The cylinder must be transparent and include a black graduated scale.
3. It is important that the components do not contain latex.
4. The piston must be transparent, made of low-density polyethylene.
5. The piston stroke will be smooth if there is a sealing collar that includes 2 rings. There must be a special lubricant between them.
6. It is necessary that there is a retaining ring that will not allow the piston to come out of the cylinder.
7. The expiration date should be taken into account. Usually it is 5 years.

Theraflu ExtraTab

These fever tablets contain paracetamol, which reduces fever well. In addition, Theraflu ExtraTab contains phenylephrine (a vasoconstrictor) and chlorphenamine (an antihistamine). Therefore, the drug has a complex effect - it relieves swelling during a runny nose and reduces fever. Contraindications to taking Theraflu ExtraTab include stomach ulcers.

Theraflu extratab

Novartis Pharma Services AG (Novartis Pharma), Switzerland

Symptomatic treatment of infectious and inflammatory diseases (ARVI, including influenza), accompanied by high fever, chills, headache, runny nose, nasal congestion, sneezing, muscle pain.
from 148

362

• Like
• Write a review

Ibuklin

This is a complex antipyretic drug - here paracetamol and ibuprofen (antipyretic and NSAID). You can buy Ibuklin without a prescription; the product reduces fever well, relieves cold symptoms, reduces inflammation and body aches, and improves overall well-being. “Ibuklin” begins to act 20 minutes after administration, and the effect lasts 6-8 hours. Contraindications: liver and kidney diseases, gastrointestinal problems (ulcers, gastritis). Ibuklin should not be taken with alcohol.

Ibuklin

Dr. Reddy's Laboratories, India

- symptomatic treatment of infectious and inflammatory diseases (colds, flu), accompanied by fever, chills, headache, muscle and joint pain, sore throat;
- myalgia; - neuralgia; - back pain; — joint pain, pain syndrome in inflammatory and degenerative diseases of the musculoskeletal system; - pain from bruises, sprains, dislocations, fractures; — post-traumatic and postoperative pain syndrome; - toothache; - algodismenorrhea. The drug is intended for symptomatic therapy, reducing pain and inflammation at the time of use, and does not affect the progression of the disease. from 78

775

• Like
• Write a review

Maxicold

The drug "Maxicold" contains paracetamol. This antipyretic drug perfectly relieves all symptoms of ARVI. In addition to Maxicold, you can buy Maxicold Rhino at the pharmacy, which will effectively relieve a runny nose and swelling of the nasal mucosa thanks to phenylephrine and pheniramine (vasoconstrictor and antiallergic effects). Maxicold contains vitamin C, a natural antioxidant that strengthens the immune system and helps the body fight colds.

Maxicold

JSC Pharmstandard-UfaVITA, Russia

- symptomatic treatment of infectious and inflammatory diseases (including influenza and other acute respiratory viral infections (ARVI)), accompanied by fever, chills, nasal congestion, headache, pain in the bones and muscles, in the throat and sinuses.
from 39

391

• Like
• Write a review

Maxicold Rhino

OJSC Pharmstandard-Leksredstva, Russia

- symptomatic treatment of colds, acute respiratory viral infections, flu, accompanied by high fever, chills, headache, runny nose, pain in the sinuses and throat, nasal congestion, sneezing and pain in muscles and joints.
from 53

408

• Like
• Write a review

How to help a child’s body fight infection?

Regardless of whether you follow the recommendations on what temperature to lower in children, you must take care to create the necessary conditions for the patient. All family members should improve the quality of personal hygiene: wash their hands, wear disposable gauze bandages, etc. You also need to provide the child with separate cutlery and dishes.

Recommendations for a speedy recovery:

1. A sick child must remain in bed.

2. It is necessary to ventilate the room in which the baby is located (the influenza virus and other microorganisms are concentrated in musty air).

3. Care should be taken to humidify the air (at the same time, the mucous membranes of the nose and larynx do not dry out; this improves local immunity and promotes well-being).

4. You should ensure that you drink plenty of fluids (virus breakdown products are eliminated through the kidneys, which reduces the load on the body).

5. The baby’s clothes should be light, preferably made from natural fabrics.

6. It is considered normal for a baby to have no appetite. You should avoid spices, citrus fruits, and dairy products, which can cause irritation of the gastric mucosa. A hot bath at a high temperature is not the most pleasant feeling, but cool (not cold) water can help normalize the indicators.

7. It is recommended to use the bath together with antipyretics, and not instead of them. You can also get some relief by applying a cool compress to your forehead.

Rinza

Rinza tablets are a complex drug. The product contains caffeine, which enhances the antipyretic effect and improves metabolic processes. Paracetamol helps reduce fever and relieve muscle pain. Phenylephrine relieves swelling of the nasal mucosa, chlorphenamine is an antihistamine against inflammation. "Rinza" relieves cold symptoms for 12 hours. This drug is contraindicated for pregnant women, hypertensive patients, patients with atherosclerosis, those treated with antidepressants, people with kidney and liver diseases; alcohol should not be taken while being treated with Rinza.

Rinza

Unique Pharmaceutical Laboratories, India

- symptomatic treatment of “colds”, acute respiratory viral infections (including influenza), accompanied by fever, pain, and rhinorrhea.
from 64

659

• Like
• Write a review

Aspirin

Aspirin can be bought both in regular tablets and in effervescent form. This is an NSAID whose active substance is acetylsalicylic acid. Aspirin has a strong antipyretic effect, it is an excellent pain reliever, while the anti-inflammatory effect of the drug is very weak. After taking Aspirin, relief occurs within 15 minutes (faster if these are effervescent tablets). But you need to remember that Aspirin is not the safest drug for fever. Allergies often occur to it; asthmatics, allergy sufferers and those who have problems with the gastrointestinal tract and liver should not drink it. It is prohibited for children under 15 years of age and pregnant women to take Aspirin with alcohol.

Aspirin

How to prepare the mixture

To create a lytic mixture, all its components are combined together. It is then distributed intramuscularly (in the form of injections) or orally (in the form of tablets).

For injection

When preparing a lytic mixture for injections, the following is injected into the syringe:

1. 2 ml analgin.
2. 2 ml papaverine.
3. 1 ml diphenhydramine.

The sequence of drugs taken does not change.

If it is incorrect, the following happens:

• weakening of the immune system;
• loss of sensitivity to antipyretic drugs;
• harm to the body.

For oral administration

The tableted version of the lytic mixture is better than the injectable one, since after the onset of an allergy it is always possible to do a gastric lavage. The solid form of the combination medicine for high fever is made from the same drugs that are included in the liquid one. Tablets (1 piece each) are crushed or drunk whole. Their effect appears only after 30-60 minutes.