Injection of hyaluronic acid into the face: cost, types, contraindications

The effect of hyaluronic injections in the face

Contour plastic surgery with hyaluronic acid is a procedure during which a cosmetologist injects filler under a wrinkle or skin fold and fills the insufficient volume with the drug. This allows you to model your appearance, correct facial asymmetry, smooth out wrinkles, scars, scars, moisturize and rejuvenate the skin.

Hyaluronic facial injections are also popular among women who want to increase the size and volume of their lips.

To prevent pain and discomfort, half an hour before the injections, the cosmetologist applies an anesthetic cream to the affected area.

The result of contouring with hyaluronic acid is noticeable immediately after injection correction, but the final assessment of the result can be made in a couple of days, after the slight swelling in the injection area has subsided.

Carrying out the procedure

Today, the use of hyaluronic acid fillers is one of the safest and fastest methods for solving aesthetic and some medical problems.

The duration of the procedure is from 5 to 60 minutes. On average - half an hour. Pain relief is by application, and some fillers include Lidocaine. Before the session, the doctor cleans and marks the face, places dots in the areas where the drug is administered. Photos may be taken to compare the condition of the problem area before and after the intervention. The ampoule is shown to the patient - its expiration date, integrity of the packaging, dosage. After this, the filler is injected in a targeted manner using a very thin needle, for example, under a wrinkle. Sometimes the drug is administered perpendicularly - this enhances the effect due to the formation of a reinforcing frame.

After the session, a facial massage is performed to evenly distribute the filler. The achieved effect is fully manifested after two weeks, when the skin is enriched with moisture.

Who is recommended for facial hyaluronic acid injections?

Contour plastic surgery with hyaluronic acid is recommended for patients with the following problems:

• deep nasolabial folds and “crow’s feet” (wrinkles in the corners of the eyes);
• horizontal and vertical wrinkles on the forehead;
• sagging cheekbones, sunken cheeks;
• loss of elasticity and firmness of facial skin;
• asymmetry of facial features;
• irregular chin shape;
• unclear lip contours, their inadequate volume;
• signs of photoaging of the epidermis;
• dry and dehydrated facial skin.

Contour plastic surgery with hyaluronic acid fillers is the fastest, most delicate and highly effective way to eliminate the above-mentioned shortcomings, which negatively affect not only the patient’s appearance, but also his internal state, causing the development of numerous complexes.

Facial contouring with hyaluronic acid: types and areas of treatment

The popularity of facial contouring is explained by the absence of complications and the immediate effect - rejuvenation and renewal of the face.

Hyaluronic acid injections for the face are performed on the following areas:

• on the lips – the procedure is carried out to increase the size of the lips, give them volume, and correct the contour. Beauty injections into the lips help eliminate wrinkles around the mouth, scars after injuries and surgical interventions, as well as solve the problem of drooping corners and asymmetry of the lips;
• on the nasolabial folds - injections of hyaluronic acid into the face eliminate networks of facial wrinkles and age-related skin creases in the area connecting the wings of the nose and the chin;
• on the cheekbones – correct congenital or acquired insufficient expression of the zygomatic arches by increasing them;
• chin – hyaluronic injections for the face help change the size and shape of the chin, which ensures its flawless and harmonious appearance;
• on the forehead - eliminate deep vertical and horizontal expression wrinkles, the interbrow fold;
• on the nose – hyaluronic injections for the face correct the shape of the nose, improve its proportions: eliminate asymmetry, straighten the bridge of the nose, correct the tip and wings;
• on the ears - they replenish the volume of the earlobes when they sag, thereby rejuvenating them, eliminating traces of injuries, sprains after wearing massive earrings;
• in the periorbital area – smooth out the relief of the skin around the eyes, successfully replacing surgical blepharoplasty;
• on the body – contouring with hyaluronic acid allows you to visually model your figure and mask aesthetic skin imperfections on different parts of the body – cellulite pits, atrophic scars, protruding blood vessels of the arms, etc.
• on the genitals - contouring of intimate areas with hyaluronic acid improves their aesthetic appearance and functionality. It is relevant for ptosis and laxity of the labia, birth and postoperative defects, insufficient accessibility of the clitoris, its severe hypoplasia, hypermobility of the urethra and other pathologies.

The above areas are the most popular among patients who undergo beauty injections. Hyaluronic acid injected into problem areas allows you to correct any defect and restore your former aesthetic appeal.

Main types of fillers

The advantages of hyaluronic fillers for the face and body are that hyaluronic acid is a substance contained in skin cells and is responsible for retaining moisture in the intercellular space. With age, its synthesis slows down, and a deficiency of this substance develops. The skin becomes less elastic, dry, wrinkles and other imperfections appear. Fillers replenish the deficiency of hyaluronic acid, restoring skin elasticity, beautiful color and pleasant texture. Moisturizing occurs, the production of elastin and collagen is stimulated, and regeneration processes begin. Moreover, the drugs have a gel structure, due to which they fill the intercellular space well and are slowly absorbed (biodegradation takes from 6 to 24 months).

Types of hyaluronic fillers

The results of recent studies indicate that the optimal concentration of hyaluronic acid in filler is 22 mg/g. Preparations based on it also contain a stabilizer. Its concentration is considered optimal at the rate of 0.5 mg/g. Most often, the stabilizer is BBDE, that is, butanediol diglycidyl ether, less often - DVS (divinyl sulfone). It is the concentration of the stabilizer that provides the desired cosmetic effect, but the higher it is, the higher the risk of an undesirable consequence in the form of an allergic reaction, since these substances are no longer “native” to the skin.

Fillers are divided into:

• Monophasic (hyaluronic acid content – ​​15-26 mg/g). Examples: Teosyal, Juviderm, Stylage. Evenly distributed in the folds of the skin and under it. They are distinguished by elasticity, are easier to insert under the skin and are corrected after insertion by manual action. Secondary correction after use is almost never necessary. Biodegradation occurs evenly. They are used to correct and enlarge lips, fill wrinkles, including facial wrinkles, post-acne, scars, and improve skin tone.
• Biphasic (GK – 22-23 mg/g). Examples: Restylane, Perfectha Derm. They allow you to work with larger-scale imperfections than single-phase ones. They have a high density, so manual correction is difficult, they have a smooth consistency, and are more difficult to insert and distribute under the skin. Biodegradation occurs unevenly. Primary – up to 30%, so contour plastic surgery requires correction after some time. The main advantage is long-term preservation of the effect due to high density. Even if deep lifting was performed, the primary result will last up to 1 year. Used to correct and lift the oval of the face, fill deep wrinkles, correct the tip and back of the nose, chin, cheekbones, and lip modeling.

Hyaluronic injections for the face: procedure progress

First of all, the cosmetologist needs to talk with the patient and find out what result he expects from contour plastic surgery. The doctor selects the most suitable filler and outlines the injection area.

Immediately before the procedure, the correction area is thoroughly cleaned and disinfected, and a cream with an anesthetic effect is applied to the skin.

The filler is injected subcutaneously using a syringe or a special cannula. Injections of hyaluronic acid for the face in various areas require the use of certain techniques:

• To correct wrinkles, liquid fillers are injected under the skin, linear filling or a delicate technique is used - blanching (suitable for eliminating wrinkles in the periorbital area);
• To give cheekbones, chin and other areas additional volume, softlifting with high-density fillers is used.

The average duration of injection correction is 30-60 minutes. After injections, slight swelling and redness of the skin may appear. These symptoms disappear on their own after a couple of hours.

How to use hyaluronic acid at home

Procedures and cosmetics can be quite expensive, so many women resort to using homemade cosmetics. To do this, you will need to purchase sodium hyaluronate powder at the pharmacy and prepare a solution for external use.

To do this, you need to dilute 2 g of the active substance in 30 ml of warm drinking water. leave to infuse for 40-60 minutes. The finished solution can be used as a cream. It should be applied to previously cleansed skin. Apply any other anti-aging product of similar effect on top.

Who should not receive hyaluronic acid injections in the face?

Contouring with hyaluronic acid fillers is contraindicated in the presence of the following conditions:

• tendency to form keloid and hypertrophic scars;
• hemophilia;
• viral and fungal dermatological diseases;
• diabetes mellitus type I and II;
• hemocoagulation disorders;
• chronic diseases in the acute stage.

Hyaluronic injections for the face should not be performed on pregnant and lactating women, or during menstruation.

Immunotropic properties of various fractions of hyaluronic acid

It is known that the biological properties (including immune activity) of HA vary depending on its molecular weight. Low molecular weight fragments of HA, formed during inflammation and tissue damage under the influence of bacterial hyaluronidases and free radicals, have pro-inflammatory and immunostimulating properties [28, 30]. Tetra- and oligosaccharides of HA at the site of injury bind to the receptors CD44, RHAMM, LYVE-1, TLR2 and TLR4 located on the surface of various immunocompetent cells (monocytes, T-lymphocytes, macrophages and others), which leads to intracellular induction of the synthesis of proinflammatory cytokines ( macrophage inflammatory proteins: MBB-1a and MBB-1b; monocyte chemotaxis protein 1; interleukins: IL-8, IL-12, IL-1b; tumor necrosis factor: TNF-a) and the development of a cascade of inflammatory reactions [32]. Termeer et al. [45] showed that tetra- and hexasugars of HA have immunostimulating activity and induce immunophenotypic maturation of monocyte dendritic antigen-presenting cells of the skin. In another study, Goldstein et al. [47] showed that HA fragments with a molecular weight of 135 kDa induce the maturation of dendritic cells and stimulate the development of alloimmunity, for example, during organ transplantation. Small fragments of HA (tetra- and hexasugars) lead to an increase in the size of dendritic cells and increase their production of the cytokines IL-1b, TNF and IL-12 [46].

At the same time, high molecular weight hyaluronic acid is an anti-inflammatory agent, leads to a decrease in the level of pro-inflammatory cytokines and plays an active role in maintaining immune tolerance [24], promotes the induction of regulatory T cells [25], suppresses the phagocytic activity of monocytes [31] and the antigen-antigen reaction. antibody [29], prevents the activation of lymphocytes [27].

Hyaluronic acid for the face (injections): cost at the Sharm Gold clinic

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Frequently Asked Questions About Hyaluronic Acid Injections

Injection facial correction is practically painless thanks to the use of topical anesthesia and the use of a very thin needle to administer the drug.

In recent years, the demand for hyaluronic acid injections for the face has increased sharply. The price in Moscow for these procedures is quite affordable for everyone, since the doctor can select a filler taking into account the patient’s financial capabilities.

The result of the procedure lasts from 1 to 2 years. If desired, injections of hyaluronic acid into the face can be repeated.

There is no risk of developing negative consequences of the procedure. Over time, hyaluronic acid “resolves” in tissues on its own.

No special preparation is required for the procedure. A few days before the injections, it is enough to refrain from alcohol, smoking, caffeine-containing drinks, avoid taking anticoagulants, and visiting beaches and solariums.

Anti-inflammatory and regenerating mechanisms of action of GCs

The physiological role of HA has been well described by many researchers [8–10]. In general, HA can participate in various cellular processes (cell differentiation, proliferation, etc.) and perform physiological functions (lubrication, hydration balance) [9, 10]. HA has unique rheological properties and is an integral part of articular cartilage; the important role of HA in the functioning of joints, not only healthy ones, but also joints with OA [11], as well as other body tissues, has been well studied [12]. Studying the pharmacological action of GC, E. Maheu [13], GM Campo [14] and J. Jerosch. [15] in their studies proved that GC reduces the activity of proinflammatory mediators that produce neuropeptides released by activated synovial cells. The authors also described the interaction of HA with pain receptors and its analgesic properties.

LW Moreland [10] noted in his study that HA can reduce the mechanosensitivity of pain receptors. GC may also reduce OA pain by reducing the synthesis of prostaglandin E2 and bradykinin.

In OA, synovitis plays an important role in inducing pain, swelling and stiffness [16], and the severity of synovitis correlates with a high risk of progression to knee OA [17]. A study was conducted that showed that GC inhibits the activity of matrix metalloproteinases and aggrecanases, which are at least partially involved in the degradation of OA cartilage as a result of their induction by proinflammatory cytokines such as interleukin-1 (IL-1) [18]. . Therefore, it is hypothesized that GC modifies structural joint damage and the rate of progression of OA in addition to its symptom-modifying effect [19].

Regarding the reparative function of HA, JL Cook et al. [20] suggested that intra-articular administration of GC has a direct effect on chondrocytes or synoviocytes and the production of Transforming growth factor beta (TGF-β), basic fibroblast growth factors (FGF) and insulin-like growth factor (Insulin-β). like growth factor, IGF). Histological data confirmed that HA prevents cartilage degradation and may promote cartilage regeneration. Other authors [14] have also provided evidence that GC treatment mitigates synovial hypertrophy and increases the number of synovial fibroblast-like cells while reducing the number of macrophages, lymphocytes, mast cells and adipocytes. HA, according to them, provides cartilage protection by suppressing the production of proinflammatory cytokines, free radicals and proteolytic enzymes in the synovial fluid.

A large number of clinical studies have found that GC reduces the progression of OA. GC is a slow-acting drug that can be used prophylactically or therapeutically as an anti-inflammatory symptom-modifying drug [20, 21].

Several clinical studies have found that intra-articular HA injections slow joint space narrowing on x-ray and stop the progression of cartilage degeneration on subsequent arthroscopy [22, 23].