Nurofen: what kind of pain it saves from and how quickly it brings down the temperature

What is Nurofen syrup and tablets for?

The action of Nerofen is explained by the presence of ibuprofen in the composition, which, by acting on the thermostat in the brain, relieves fever and returns the temperature to normal values.

In addition, ibuprofen inhibits the synthesis of prostaglandins, which are mediators of pain. Which explains its analgesic effect. This is why Nurofen is indicated for:

high body temperature;
toothache;
headache;
muscle pain;
for adverse reactions after DTP.

Adverse reactions

Side effect of the drug is visual disturbances

Like any medicine, Nimesil may have side effects:

allergic reactions - sweating, rash, itching, erythema, anaphylactoid reactions, dermatitis, urticaria, erythema multiforme, angioedema, Stevens-Johnson syndrome, Lyell's syndrome;
hematopoietic disorders - eosinophilia, pacitopenia, anemia, thrombocytopenia, hemorrhagic syndrome, thrombocytopenic purpura;
visual disturbances – blurred vision;
disorders of nervous activity - feelings of fear, dizziness, headache, nightmares, drowsiness, nervousness, encephalopathy;
circulatory disorders - hot flashes, tachycardia, arterial hypertension, sudden changes in blood pressure;
digestive system disorders - nausea, diarrhea, vomiting, flatulence, constipation, abdominal pain, gastritis, dyspepsia, tarry stools, stomatitis, bleeding from the digestive tract, gastric perforation or ulcer, duodenal perforation or ulcer, hepatitis, cholestasis, jaundice, increased levels of liver enzymes;
breathing disorders - shortness of breath, attacks of bronchial asthma;
general disorders – asthenia, general malaise, hypothermia;
disorders of the genitourinary system - renal failure, hematuria, urinary retention, dysuria, oliguria, interstitial nephritis;
other disorders – hyperkalemia is possible.

After how many hours can Nurofen be given?

Due to the fact that the drug is quickly and almost completely absorbed from the gastrointestinal tract, its maximum concentration in human plasma is reached after 30 minutes. This suggests that after taking the drug on an empty stomach, the patient’s temperature should begin to decrease within 40 minutes. When taking a single dose of the drug after a meal, the antipyretic effect should appear after an hour.

If the temperature has not started to decrease after an hour, you can give another antipyretic drug. In this case, it is better to give preference to paracetamol. Nurofen can be taken again no earlier than 4 hours after the first use.

The same dosage regimen also applies in the opposite direction, when the question arises of how long after paracetamol can be taken Nurofen. If taking paracetamol after an hour does not work, you can switch to ibuprofen.

How to take Nurofen?

Nurofen must be used exactly as indicated in the instructions for the drug or as prescribed by your doctor. Do not take more than recommended dosage or exceed the recommended duration of use. Always take only the minimum effective dosage.

The maximum dosage of Nurofen for adults is 800 mg at a time or 3200 mg per day (4 maximum doses). Use only the minimum amount needed to relieve pain, inflammation or fever.

The dosage of Nurofen for a child depends on his age and weight. Therefore, taking the drug for children is possible only as prescribed by a doctor.

In order to protect the stomach from the irritating effects of Nurofen, you can combine taking the drug with food or milk.

If you purchased the medicine in suspension form, shake the bottle thoroughly before measuring the dose using a measuring spoon or syringe.

Be careful!

If you take Nurofen for a long time, you must undergo regular tests and a medical examination.

The medicine should be stored at room temperature away from moisture, heat and sunlight. The drug in the form of a suspension cannot be frozen.

Before use, be sure to read the instructions and consult your doctor.

If Nurofen does not bring down the temperature: what to do

When the thermometer rises above 39˚C, absorption of substances from the stomach may stop. This means that taking medications orally may not have an effect. This happens especially often when the patient washes down the tablet or syrup with cold water. Once in the stomach, cold liquid forces the vessels of the gastric walls to contract, as a result of which they cannot fully pass substances through their walls.

In this case, doctors recommend giving preference to rectal suppositories at high temperatures exceeding 39˚C. The suppository, once in the rectum, quickly dissolves, and ibuprofen immediately enters the bloodstream through the intestinal walls. After 30-40 minutes, the patient’s temperature begins to decrease.

Nimesil and alcohol

Nimesil and alcohol are incompatible; taking them together is strictly prohibited. Why? Both alcoholic drinks and Nimesil reinforce each other and are hepatoxic, that is, they affect the liver and can lead to severe disorders of its functioning: the development of granuloma, acute hepatitis and cirrhosis. Also, the combination of the drug and alcohol provokes fluid retention in the body and high blood pressure. The functioning of the gastrointestinal tract is also disrupted. Alcohol irritates the gastric mucosa, causing gastritis and ulcers. Internal bleeding may occur as a result of perforation of the wall of the stomach and intestines.

Do not take Nimesil with alcohol

They try not to prescribe Nimesil to patients with pathologies of the cardiovascular system and blood. Ethyl alcohol causes vasospasm, which increases the load on the heart, and simultaneous use of the drug can lead to acute heart failure or death. For patients who suffer from alcohol addiction, Nimesil is contraindicated, since the body is weakened, the risk of complications increases significantly. Also, the suspension is not recommended to be taken during a hangover.

How many times can Nurofen be given to a baby?

The effect of the drug begins an hour after the first dose. The decrease in temperature can continue for up to half an hour until the values drop to normal levels. The antipyretic effect can last up to 8 hours. However, with severe inflammatory processes, the fever may return after 4-5 hours. An infant can be re-given a single dose of the drug both in the form of suppositories and in the form of syrup after 4 hours if the temperature begins to rise again. A baby can receive up to 5 permissible single doses per day.

Analogues of the drug Nimesil

Analogs

In pharmacies you can find quite a large number of Nimesil analogues. The active ingredient of the drug - nimesulide - is superior in action to popular drugs from the NSAID group (Ibuprofen, Diclofenac). However, similar substances in the composition do not guarantee the same effect as Nimesil. That is why there is no need to self-medicate - consult a specialist.

Nise is an effective pain reliever and an analogue of Nimesil. The main difference is that Nise is available in the form of a topical gel and tablets;
Nimesulide and Nemulex - the medicine is not inferior to Nimesil in terms of effect strength, but costs less;

Aponil is related to NSAIDs and has a pronounced anti-inflammatory effect, but weaker than Nimesil;
Nimulid - the medicine is produced in several forms: tablets, suspension, injection solution, gel;
Prolide - the product is available in the form of fast-acting tablets. Compared to Nimesil, it has fewer side effects.

Also, the pharmaceutical market is ready to offer: Ameolin (tablets), Affida Fort (granules for preparing a suspension), Nigan (tablets), Nimegesic (tablets, suspension), Nimesin (tablets), Nimegesic (tablets, granules), Nimujet (injection solution), Nimujet (tablets), Pansulide (tablets), Remesulide (tablets), Sulidin (gel), Taro-Sanovel (tablets).

The use of analogues should be agreed with the attending physician.

Which is safer Nurofen or paracetamol

Ibuprofen, which is part of the drug, is contraindicated for people with chronic bronchial diseases, in particular asthma. In addition, Nurofen should not be taken by patients with intolerance to the active substance, pregnant women, patients with heart failure, diagnosed liver failure and gastrointestinal bleeding.

Contraindications to taking paracetamol are the neonatal period, individual intolerance to the drug, and gastric ulcers, including erosion and inflammation of the gastrointestinal mucosa.

Contraindications

history of hepatotoxic reactions caused by the active substance;
bronchospasm, urticaria, rhinitis associated with the use of acetylsalicylic acid or other non-steroidal anti-inflammatory drugs in the anamnesis;
concomitant use of drugs with potential hepatotoxicity;
condition after coronary artery bypass surgery;
inflammatory bowel diseases (ulcerative colitis, Crohn's disease) in the acute stage;
increased body temperature in infectious and inflammatory diseases;
exacerbation of a peptic ulcer, a history of ulcers, perforation or bleeding in the digestive tract;
a combination of bronchial asthma, nasal polyposis and intolerance to non-steroidal anti-inflammatory drugs;
bleeding of cerebrovascular or other localizations; diseases accompanied by pathological bleeding;
decompensated heart failure;
severe blood clotting disorders;
decompensated renal failure, hyperkalemia;
liver diseases;
liver failure;
alcoholism, drug addiction;
pregnancy or lactation;
age under 12 years;
hypersensitivity to the components of the drug.

The decision to prescribe the drug Nimesil remains with the attending physician.

Release forms

Nurofen tablets 200 mg No. 6, No. 12, No. 24.
Nurofen children's TB 200 mg from 6 years No. 8, from 12 years No. 12
Nurofen Forte TB 400 mg No. 12.
Nurofen Express Forte capsules 400 mg No. 10, No. 20.
Nurofen Express Ultracap 200 mg capsules No. 10.
Nurofen Intensive TB No. 6.
Nurofen Cold Flu TB No. 12.
Nurofen for children rect suppositories No. 10
Nurofen for children suspension 100ml (strawberry, orange)
Nurofen Forte for children suspension 100ml (orange, strawberry)

Symptoms of an overdose of Nurofen

You should immediately stop using Nurofen and consult a doctor immediately if you experience the following symptoms that may indicate an overdose of this drug:

changes in vision (decreased clarity, distorted colors);
shortness of breath (even with light exertion);
swelling of the body or rapid weight gain;
the first sign of any skin rash, no matter how mild;
signs of stomach bleeding - bloody or tarry stools, coughing up blood, or vomit that looks like coffee grounds;
evidence of liver problems - nausea, pain in the upper abdomen, feeling tired, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
signs of kidney problems - infrequent, little or no urination, painful or difficult urination, swelling of the legs or ankles, feeling tired or short of breath;
low red blood cell count (anemia)—pale skin, dizziness or shortness of breath, fast heartbeat, trouble concentrating;
for severe skin and mucous membrane reactions—fever, sore throat, swelling of the face or tongue, burning eyes, skin tenderness, followed by a red or purple skin rash that spreads, especially to the face or upper body, and causes blistering and peeling.

Application

Increased temperature that needs to be brought down; pain, especially during teething - symptoms that every mother with a small child encounters. In such cases, Nurofen helps very well and in a fairly short time.

Nurofen syrup is recommended for children from 3 months, the daily dose is 20-30 mg/kg body weight, it should be divided into equal doses and drunk with an interval of 6-8 hours between doses. For children from 3 months of age, Nurofen suppositories are also used, 1 suppository. If necessary, take the drug again, but no more than 3 suppositories per day.

For children from 6 years of age, Nurofen Forte suspension is used, the dosage is the same - 20-30 mg/kg body weight, the daily dose is divided into equal parts. For the same age category, you can use Nurofen TB for children 200 mg (from 6 years old). You should take 1TB. The time between doses is at least 6 hours. For adults and children over 12 years of age, Nurofen is recommended at a dosage of 200-400 mg per dose with an interval of 6-8 hours.