Nimesil or Meloxicam: differences in compositions, reviews from doctors and indications for use

Treatment with drugs from the group of nonsteroidal anti-inflammatory drugs (or NSAIDs) has been gaining popularity in recent years among both adults and children.

In this regard, pharmaceutical companies strive to create new medicines and improve old ones. Meloxicam is one of the most effective drugs in the NSAID group, and the list of diseases for which it can be prescribed exceeds more than a dozen.

Despite its effectiveness, there are analogues of the drug that may cost less, but are not inferior in effectiveness.

Pros and cons of Movalis

If we consider the mechanism of action, the active substance meloxicam is involved in the process of selective inhibition of prostaglandins, which, in turn, cause inflammation and, as a consequence, other symptoms. In modern medicine, two types of NSAID drugs are used - COX-1 and the more modern COX-2, which includes Meloxicam.

One of the advantages is that the drug has fewer side effects.

It is for this purpose that a standard regimen for administering Movalis has been developed, when it is better to give injections in the first days of the disease, which allows maximum impact on the source of inflammation and pain, after which a course of the drug in tablets is prescribed. This makes it possible to reduce the risk of acute ulcers or erosion of the mucous membrane in the stomach, which provoke bleeding.

Meloxicam also causes less nausea, vomiting, and abdominal pain. Use via injections and tablets allows you to increase the course of treatment with Meloxicam, while its analogue Diclofenac is allowed to be taken an order of magnitude less.

In different regions of our country, prices may vary, but it will be difficult to find a drug cheaper than 400 rubles. In this case, the course of treatment is designed for 3 injections and a course of tablets, that is, you need to buy two packages of Movalis. There are also limitations in application. Movalis should not be prescribed to pregnant women, during lactation and children under 12 years of age.

You can replace Movalis with two options - find substitute analogues of Movalis with the same active substance or select an analogue from the NSAID group, which has a different composition.

Analogues with the active substance meloxicam

Meloxicam, as an active substance, is included in the following drugs:

• amelotex;
• meloxicam;
• arthrozan.

The cheapest analogue of Movalis is Meloxicam itself, which is produced by several enterprises. The release form is tablets of 7.5 and 15 mg, as well as ampoules for injection. To replace Movalis with Meloxicam, you must inform your doctor, who will prescribe the duration of the drug and dosage.

Before using drugs containing meloxicam (Amelotex, Movalis), you need to familiarize yourself with the list of contraindications. It is prohibited to prescribe the medicine in the presence of hypersensitivity to the active substance, in case of peptic ulcer of the stomach and duodenum during an exacerbation.

Since the drugs have a powerful effect and cause a number of side effects, it is prohibited to use Meloxicam in case of renal failure, bleeding in the gastrointestinal tract, liver failure, or hyperkalemia. When prescribed in the elderly and with weak liver and kidney function, you need to undergo additional examinations and strictly follow the doctor’s recommendations.

Meloxicam analogs

In general, the NSAID group contains an extensive list of drugs with similar indications. If we take analogues of the active substance, then its synonymous drugs are Ibuprofen, Nimesulide, Diclofenac.

These drugs are used to treat diseases of the musculoskeletal system, prescribed for arthrosis, spondylitis, osteoporosis, epicondylitis, rheumatism and other pathologies with severe pain.

Diclofenac

Diclofenac, as an analogue of Movalis, has a number of disadvantages. Due to the strong effect on the gastrointestinal tract, kidneys and liver, the course of its use is limited to injections up to 5 days, a course of tablets - up to 2 weeks. Due to the effect on the mucous membrane of the stomach and intestines, tablets are rarely prescribed.

There are a number of advantages that Diclofenac has. Diclofenac injections have a powerful analgesic effect, that is, Movalis will not be able to relieve pain so quickly if the sciatic nerve is pinched or trigeminal neuritis.

Another plus is a large number of ointments and gels for local use for injuries and inflammations. The drug is also affordable.

Diclofenac has analogues that contain it; its synonyms are Diclofenac, Voltaren, Diclak, Ortofen.

Nimesulide

To treat many inflammations and injuries, an analogue of Movalis, Nimesulide, is often used. In practice, its analogue is also called Nise, although the composition of the drug is Nimesulide.

The drug belongs to the group of NSAIDs (sulfonanilides), and the action is associated with COX-2.

Nise relieves pain well, relieves swelling and is available in several forms, which makes it possible to prescribe it for many pathologies.

Contraindications and side effects allow the use of drugs containing Nimesulide only after consulting a doctor. Analogs of Nimesulide are Nise, Nimesil, Nimid.

Ibuprofen

Ibuprofen is a rare drug prescribed for young children. Unlike other NSAIDs, Ibuprofen is less dangerous and at the same time relieves inflammation better. Ibuprofen is used more to treat high fever and reduce inflammation. The downside is less pain relief for injuries and joint diseases.

Indications for Ibuprofen:

1. Diseases associated with inflammation in the musculoskeletal system: arthritis, arthrosis, spondyloarthritis. Prescribed for ankylosing spondylitis, epicondylitis, periarthritis.
2. The presence of pain due to injuries, pinched nerves, headaches, pain during menstruation.
3. Increased body temperature due to influenza, acute respiratory infections, ARVI, and infections.

The product is used in the form of tablets, ointments, powder and injections.

Ketorolac

Ketorolac is considered the most powerful drug in the NSAID group; it is included in the list of emergency medicines; instructors recommend carrying it in a car in case of an accident.

The drug is rarely prescribed for the treatment of chronic pathologies of the joints and spine. Ketorolac is more used to relieve pain from injuries, after operations and in cases of acute pain.

An analogue of Ketorolac is Ketanov.

Whatever drug you choose, do not forget that all medications have their side effects. To choose a drug that is right for you, you should consult a doctor, because only a specialist knows what will help best.

Indications

If you carefully study the official instructions for Movalis, it will not be written anywhere about protrusions and hernias. But it is enough for us that the indications include a disease of the musculoskeletal system and acute back pain. Protrusions and hernias in the form of exacerbation fit well into this definition. What other indications exist for the use of Meloxicam? We can briefly list them:

• all inflammatory rheumatic diseases of connective tissue, such as spondyloarthritis, rheumatoid and psoriatic arthritis;
• osteoarthritis with an inflammatory component;
• glenohumeral periarthritis;
• compression of the nerve roots is what causes protrusions and hernias. Compression radiculopathy is manifested by acute, piercing pain in the back and leg (sciatica, lumbago, radiculitis);
• various plexites.

Movalis is also used for acute periods of sports injury, for sprained ligaments.

Nimesil or Diclofenac?

Nonsteroidal anti-inflammatory drugs are successfully used to relieve pain, swelling associated with inflammation, and spasms.

The drugs Nimesil and Diclofenac are quite popular representatives of NSAIDs, often included in the symptomatic treatment of a number of joint diseases, lesions of the upper respiratory tract, and postoperative conditions.

Despite their belonging to the same pharmacological group, the action of each drug has its own characteristics that must be taken into account when choosing therapy.

There are contraindications, use after consulting your doctor

What is the difference?

To identify the differences, it is necessary to consider the composition of Nimesil and Diclofenac, to compare the mechanisms for achieving the therapeutic effect of each drug.

Treatment of osteochondrosis with drugs

For patients with osteochondrosis in the acute period, complete rest and exclusion of any physical activity at the site of the lesion are indicated. To create a comfortable position and fix the affected area, special bandages and clamps are used. Patients with osteochondrosis in the neck area are advised to wear a special collar, which ensures the correct position of the vertebrae of the neck during treatment. In case of thoracic and lumbar osteochondrosis, the patient is prescribed rest and bed rest.

To treat osteochondrosis, take NSAID medications

Drug therapy for this disease includes taking drugs such as Diclofenac, Ketolarak and other drugs included in the NSAID group. If there is severe pain, the patient needs to take analgesics, for example, Flupirtine. If the pain is caused by severe muscle tension, the patient is prescribed drugs - muscle relaxants.

"Movalis" is a drug that is often used in the treatment of osteochondrosis.

Nimesulide and Meloxicam: how they differ and which is better to choose

There are many drugs whose actions are aimed at eliminating fever. Among the wide range of pharmaceuticals, Nimesulide and Meloxicam have become particularly relevant. They have a wide range of applications, their actions are aimed at eliminating fever and reducing inflammatory manifestations.

Nimesulide: description

The medicine is quite relevant and is a non-steroidal anti-inflammatory. Available in various forms: powder, tablets, gels and ointments. External options are used if there is a need to influence a clearly defined area.

Main advantages:

1. The components are aimed at eliminating inflammatory processes.
2. Wide range of applications.
3. Affordable price.
4. High efficiency parameters.
5. Minimum list of contraindications.
6. Safety of use.
7. Eliminate fever and reduce pain.

Note that there are a number of auxiliary properties that prevent excessive blood clotting and reduce the likelihood of thrombosis. It has the ability to reduce the impact of free radicals, reduces all symptoms of allergic reactions.

Meloxicam: description

It has a wide range of applications when it is necessary to reduce inflammatory processes. Used to relieve pain. It has a general strengthening, calming effect on the body. Available in the form of tablets, solutions, suppositories.

Solutions are used for injection, which guarantees a quick process of action. The active ingredients quickly penetrate connective tissues and are completely absorbed.

The level of concentration in the body does not increase even with prolonged use.

It is highly effective, so most often standard treatment is prescribed to take one tablet per day.

The duration of treatment, as well as the choice of form, is based on a study of all medical history data, on the recommendation of a doctor.

The drug is actively used for osteochondrosis, inflammatory processes, degenerative disorders in muscle tissue, and for pain attacks that arise for various reasons.

Through the active action of the main components, pain areas are almost instantly suppressed , which makes it possible to reduce their intensity. The level of spasms decreases, the general condition of the patient improves due to the calming effect.

About the disease

Osteochondrosis, a disease that affects intervertebral discs and cartilage, is quite widespread today. With the development of pathology, intervertebral discs are most often affected, which makes the daily life of such patients very difficult, because the condition of the intervertebral discs determines the mobility of the ridge, flexibility, and, most importantly, the ability to withstand heavy loads. During stress on the spine, it is the discs between the vertebrae that act as shock absorbers.

The development of osteochondrosis is the cause of the presence of certain malfunctions in the human body, which together leads to the development of this pathology.

Causes.

1. Mineral metabolism in the human body is disrupted. The amount of minerals that enter the body significantly reduces the amount of substances sufficient for the body to function normally. Such failures can occur during periods of rapid and active growth, as well as in the presence of severe overloads. The cause may also be improper distribution of physical activity, or improper execution of movements: both physical exercise and everyday activities.
2. Blood circulation in the spine is impaired, which causes insufficient nutrition of the intervertebral discs. The cause of this process can be scoliosis, as well as a sedentary and sedentary lifestyle.
3. “Fraying” of intervertebral discs and the formation of intervertebral hernia.
4. Due to the prolapse of the intervertebral disc and the formation of a hernia, the vertebrae begin to fray, forming osteophytes.

Osteochondrosis can develop as a consequence of other pathologies of the spinal column

According to statistics, almost 80% of the adult population around the world suffer from a pathology such as osteochondrosis. This disease can manifest itself in adolescence or even childhood. Research shows that boys are more susceptible to this disease than girls. Almost all people over twenty years of age have osteochondrosis to a greater or lesser extent. Osteochondrosis can manifest itself not only as lower back pain, but also as pathologies of the internal organs of a person.

Types and stages of pathology

There are a large number of types of localization of this disease. Lumbosacral osteochondrosis is the most common type of this disease and occurs in every second patient with this pathology. A quarter of all cases occur with cervical osteochondrosis . Slightly more than 10% of patients experience osteochondrosis, which affects several parts of the spine at once . This form of osteochondrosis is considered the most severe and rare.

Pharmacological marketing or two different drugs? Let's figure out which is better: Meloxicam or Movalis

The choice between Movalis and Meloxicam depends on the cost of the drugs. The pricing policy of the German company that produces Movalis is higher. Patients are trying to figure out what works better and more effectively on joints in the form of tablets, injections and suppositories.

The drugs Movalis and Meloxicam contain the same active ingredient. Meloxicam is a generic drug of Russian origin.

Is this the same medicine? Let's find out what the difference is

The active component of Movalis and Meloxicam is the substance meloxicam. The drug Meloxicam is produced by Russian companies: Alvils, Atoll, Biosintez, Altaivitamins, Dalhimpharm, Ozon, Medisorb and others. Dosage forms of the drug are rectal suppositories, tablets and solution for injection.

Movalis

Movalis is an original drug that is available in the form of rectal suppositories, tablets, and solution for injection. The product is produced by the German company Boehringer Ingelheim International, GmbH. The company has been producing medicines on the pharmaceutical market and monitoring the quality of raw materials since 1885.

The active component of Movalis undergoes a high degree of purification, which minimizes the number of side effects. All products of the German company undergo randomized clinical trials on patients. Before entering the market, the effectiveness and safety of Movalis was studied for 5 years.

In the table, see the excipients of Movalis and Meloxicam tablets. They are placed depending on the amount of substance, in descending order:

Read more about the difference between Meloxicam-Teva tablets and injections here.

Movalis tablets are not recommended for patients with lactase deficiency and milk intolerance.

Otherwise, the composition of the original German tablets differs slightly from Meloxicam.

Additional components affect the shelf life of the tablets and the distribution of the active substance evenly throughout the structure. The tablets from both companies have a convenient convex shape and a yellowish tint. The drugs have the same dosage: 1 tablet contains 7.5 or 15 mg of active ingredient.

In the composition of Meloxicam suppositories (using the example of the Dalkhimpharm company), the auxiliary components are not listed in exact quantities. The manufacturer indicates that the composition includes solid fats to obtain a suppository weighing 1.25 mg. The instructions for Movalis contain a list of auxiliary components:

Meloxicam

suppositir VR;

1. macrogol glyceryl hydroxystearate;
2. cremophor RH40.

The manufacturer of Movalis does not hide the composition of the suppositories.

These are the names of solid fats that do not affect the active substance, but are used only to give a convenient shape to the suppository. The dosage of suppositories is 7.5 or 15 mg of active ingredient. Meloxicam rectal suppositories are also available in 7.5 or 15 mg doses, but from different manufacturing companies.

The Movalis solution contains excipients:

Solution for injections

meglumine is a solvent and detoxification component;

1. glycofurfural – solvent;
2. glycine is an essential amino acid that helps the product to be adsorbed into tissue;
3. poloxamer 188 – a binder that gives the solution a uniform consistency;
4. sodium chloride and sodium hydroxide are components for stabilizing the osmolarity of the product and maintaining physiological pH;

Russian-made Meloxicam contains the same auxiliary components, but glycerol is present instead of glycine. This softens the product and allows you to maintain a high concentration of the active compound in the injection solution. Dosages of active medicinal substances for drugs in solutions are 7.5 mg or 15 mg.

What is more effective?

1. When choosing between Movalis and Meloxicam, you should pay attention to the patient’s ability to pay: the original drug costs 3 times more. During a long course of treatment, the patient may not have enough money to purchase the original.
2. Movalis tablets or injections may be better than Meloxicam due to the high-quality purification of raw materials by the pharmaceutical company.
3. Counterfeits of the original drug are common in Russia.
4. The active component of the drug is meloxicam.

Which is better: Nimesil or Meloxicam?

Both drugs have a pronounced anti-inflammatory effect. But the effect when using Nimesil is achieved thanks to the active substance nimesulide. It penetrates directly into the focus of the pathological process and acts for 6 hours.

The action of the drug Meloxicam is based on the active substance of the same name. But the effect after taking the drug comes more slowly. That is why, when you need to quickly relieve severe pain, it is recommended to use Nimesil.

Meloxicam belongs to the group of NSAIDs and has antipyretic, anti-inflammatory and analgesic effects. Unlike Nimesil, it does not have a negative effect on the liver.