Composition of Boyko's mixture, its use, indications and contraindications


Boyko's mixture is a combination of drugs that is designed to provide analgesic, mild anti-inflammatory and sedative effects. The composition of Boyko's mixture is not constant; it may vary slightly depending on the patient's indications and complaints. The classic combination of components and various variations will be discussed below. It is also worth noting that the components included in the mixture are very inexpensive, accessible, effective and have a small number of contraindications.

Application

In neurology, Boyko's mixture is used for pain syndromes of various etiologies. A mild sedative effect is also used, which can be used to improve sleep quality in dissomnia syndrome caused by a long course of the underlying disease.

The most effective use of the drug is for the following diseases and syndromes:

  • Lumbar osteochondrosis.
  • Thoracic osteochondrosis.
  • Intercostal neuralgia.
  • Vertebrogenic lumboischialgia.
  • Sciatica.
  • Severe pain syndrome with mononeuritis, etc.

Classic composition

Boyko’s mixture (composition and use may vary) is known due to the existence of a classic recipe for the base, the components of which are summarized in a table with their action and indications.


Boyko's mixture

Name of substanceQuantity, mlActionIndications
Analgin2The drug has antipyretic, anti-inflammatory and analgesic properties. The mechanism of action involves inhibition of prostaglandin synthesis after intravenous or intramuscular administration. The active substance is quickly absorbed in the body.
  • Pain of various origins;
  • fever;
  • infectious and inflammatory diseases.
Novocaine2The drug is a local anesthetic with a broad therapeutic effect. The mechanism of operation is based on blocking nerve endings and the passage of impulses along the fibers. The active substance relieves muscle spasms, excitability of the myocardium and mobile areas of the cerebral cortex. The duration of action is from 30 minutes. up to 1 hour Novocaine is used in the form of infiltration anesthesia and as anesthetic blockades.
Diphenhydramine1-2The drug has an antiallergic and analgesic effect, has local anesthetic, antispasmodic, sedative properties with a moderate antiemetic effect, reduces blood pressure and increases hypotension (if present).
  • Allergic manifestations (urticaria, conjunctivitis, rhinitis, dermatoses);
  • complex treatment of anaphylactic conditions (Quincke's edema);
  • insomnia;
  • seasickness;
  • burns;
  • animal and insect bites.
Vitamin B120,5Cyanocobalamin belongs to the group of cobalt-containing biologically active substances that participate in enzymatic reactions of transfer of hydrogen atoms and methyl group (monovalent methane radical) in plasma. Vitamin deficiency causes various types of anemia. As a result, neurological disorders appear. Used when there are signs of vitamin deficiency in the body or hematopoietic disorders.

Contraindications

There are quite a few contraindications to prescribing the drug. Among them, the first, most important role is played by intolerance to the components (primarily vitamin B12, novocaine). In case of allergic reactions, novocaine can be completely excluded from the composition. Also, you should not resort to the prescription in case of existing pathology of the hematopoietic organs (can lead to disruption of the cellular composition of the blood), severe pathology of the gastrointestinal tract, severe cardiovascular diseases, or lack of reliable allergy history.

Drug interactions

The simultaneous use of Boyko's mixture with alcohol is unacceptable.

Using the mixture simultaneously with other non-narcotic painkillers may increase the toxic effects of the latter.

Treatment with the mixture while taking contraceptives and tricyclic antidepressants disrupts metabolic reactions in the liver.

Simultaneous use with barbiturates reduces the analgesic effect of the mixture.

Use with Thiamazole and Sarcolysin leads to the development of leukopenia.

Boyko's mixture enhances the effect of muscle relaxants.

When used simultaneously with anticoagulants (heparin, warfarin), the risk of bleeding increases.

Reviews

Petrova Elena

:

I decided to work at the dacha one sunny Sunday. My back, of course, had bothered me before, but this time it was something. You can’t bend or straighten up, but the pain is such that you could even howl like a wolf. A neighbor advised me to buy the components of Boyko’s mixture at the nearest pharmacy and inject it into a soft spot in a syringe. It was released, I was able to at least wait until Monday and see a neurologist, who, among other medications, prescribed vitamin B12, which is one of the components of this wonderful remedy.

How to treat bumps on the buttocks

Regardless of the reason for which you have painful lumps after injections, they still need to be treated. “You definitely shouldn’t self-medicate, especially with “fresh” infiltrates, since any infiltrate can both resolve and fester. I’ll immediately explain what a “fresh” infiltrate is. This is a lump that you discovered immediately after the injection or is not older than 14 days. If the infiltrate is 1-2 months or more old, then the probability of its suppuration is quite small, but the probability of its complete resorption also tends to zero,” notes the specialist.

If it doesn’t reach the point of an abscess, then you can get by with fairly simple means - using gels, ointments and compresses. “What specific medication you need, the frequency and duration of its use, is determined by the doctor during an in-person visit after examination and carrying out the necessary examination methods (ultrasound of soft tissues),” says the doctor.

At home, hematomas and infiltrates can be treated with safe means. “Moderate massaging of the injection site, performing squats and applying cold compresses to the site of swelling in the first 1-2 days after its appearance is acceptable,” reminds Bulat Yunusov.

“Bumps after injections can be treated with an iodine mesh, but it is better to see a surgeon so that he can prescribe physical therapy,” the general practitioner recommends.

Physiotherapy is prescribed as an addition to the main treatment, which allows it to be shortened. Among the most effective methods are:

  • Electrophoresis
    is the penetration of medicinal drugs into the skin and soft tissues under the influence of an electric field.
  • UHF.
    “This is the treatment of infiltration with a continuous or pulsed ultra-high-frequency electric field,” comments a doctor at a Moscow clinic.
  • Phototherapy.
    Irradiation of problem areas with ultraviolet light in a narrow or wide range.

Are there any disadvantages to local anesthesia?

Local anesthesia has virtually no disadvantages. Unlike drugs that were used previously, modern anesthetics are absolutely safe, have a minimum of contraindications, are quickly eliminated from the body, and do not have a negative effect on the heart, kidneys and liver. With professional administration, the patient will not feel any pain even during long surgical procedures.

“Our clinic uses a strictly individual approach. We have selected several of the most effective and safe drugs - for each patient we select our own method, drug and its concentration, based on individual characteristics. Therefore, everyone who undergoes treatment, implantation or prosthetics at the Smile-at-Once clinic can feel completely safe.”

Zhilenko Evgeniy Aleksandrovich, Implant surgeon, periodontist, orthopedist Work experience over 17 years make an appointment

Xenon sedation or xenon therapy to prepare for main anesthesia

This is a separate type of anesthesia that can be used in combination with both local and general anesthesia (if necessary). Xenon is an inert gas that quickly begins to act and is just as quickly eliminated from the body. It has a relaxing effect: anxiety decreases, the patient relaxes. Moreover, during the operation he is fully conscious, can communicate with the doctor, and understands everything that is happening around him. The procedure can be interrupted if necessary if there is discomfort. At the same time, local anesthetics are used, since xenon itself does not have a pronounced analgesic effect.

Among the pleasant “bonuses” are saturation of cells with oxygen and restoration of metabolic processes. That is, this is not only a reduction in stress, but also a general improvement in the body’s health.

Indications and advantages of local anesthesia

Since local anesthesia is used everywhere, the indications for its use are very wide. Modern drugs are of very high quality and completely safe (especially if you use them thoughtfully, having first collected a high-quality anamnesis about the patient’s health condition). The level of stress from treatment without anesthesia, and especially with acute pain, can be prohibitive - very often after this, patients refuse to visit the dentist, causing dental problems. Do not be afraid of anesthesia - you will not receive such a “dose” of the drug that will harm you, even if you have to treat your teeth for several days in a row.

Indications for local anesthesia

  • removal of dental plaque,
  • dental treatment of any complexity,
  • performing plastic surgery on gums,
  • tooth extraction,
  • surgical operations in the oral cavity,
  • preparation and implementation of dental implantation.

Advantages

  • complete relief of any painful sensations,
  • safety, no toxic effects on the body,
  • rapid elimination from the body,
  • minimum side effects,
  • the choice of drug based on the health status and age of the patient.

Types of anesthesia in dentistry

Anesthesia in dentistry can be general or local. The first includes intravenous sedation, as well as general anesthesia. That is, the drugs do not act locally in the oral cavity, but throughout the entire body. Actually, this is ordinary general anesthesia, which is used everywhere in medicine - it’s just that certain types are used in dentistry. Local, as it is already becoming clear, includes the familiar “freezing”, which is administered by injection.

Separately, we can also distinguish xenon sedation or xenon therapy - the second name will be even more correct, since such anesthesia is used to prepare for local or general anesthesia. It allows you to reduce the level of anxiety and stress, saturates the body's cells with oxygen, due to which it has a general healing and even rejuvenating effect! It is not an independent type of pain relief, but is used in combination with other approaches.

Droppers for the treatment of osteochondrosis

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To eliminate the pain that occurs with radiculitis, many patients are literally ready to try all possible drugs in order to get the long-awaited relief. But for this there is a Boyko mixture, which includes a whole range of drugs that can fight back pain.

  • pills;
  • injections;
  • physiotherapy;
  • exercise therapy;
  • massage;
  • proper nutrition;
  • surgical intervention.

Watch the video with a set of exercises

More about IVs

One of the most important components of the treatment of osteochondrosis is the use of painkillers. They are prescribed a course. In most cases, analgin, sedalgin, and paracetamol are used. In case of a severe attack in the first days, patients are administered mixtures of medications, which include:

  • analgesics;
  • decongestant (dehydrating) drugs;
  • anti-inflammatory;
  • muscle relaxants;
  • sedatives.

Actovegin for droppers
1 or 2 ml of a 50% solution of analgin and painkillers of other groups (5-10 ml of baralgin, 20-100 ml of a 0.5% solution of novocaine) in most cases are prescribed with 20-40 ml of hydrocortisone, 10 ml of 2.4% aminophylline solution, 20-40 mg of Lasix, 1-2 ml of tranquilizers (for example, Relanium), up to 2000 mcg of vitamin B12. For osteochondrosis, droppers with these mixtures in various optimally compatible combinations are recommended twice a day.

Novocaine and its derivatives are used in various dilutions:

  • sovcaine – 0.5-10%;
  • trimecaine – 0.5-0.25%;
  • lidocaine – 0.5, 1 or 2%.

For osteochondrosis, infusions of the following mixtures are most often used:

  • 50% solution of analgin no-spa lasix 0.25% solution of novocaine saline solution;
  • baralgin relanium dexazone novocaine glucose;
  • 50% solution of analgin 2% solution of no-shpa reopirin.

Decongestant, or dehydrating, complexes are prescribed mainly for the severity of radicular syndrome. In many cases, it is advisable to use rapid-acting saluretics or dexazone. There is no consensus among experts regarding the effectiveness of these medications.

Osteochondrosis is a widespread disease. According to one neurologist, “every person over 30 has osteochondrosis, the only question is at what stage?” Naturally, for such a common illness, doctors have developed many forms of treatment, from medications (which we will talk about) to exotic physical procedures, such as mechanical stretching of the spine.

Medicines are divided into: groups (analgesics, NSAIDs, vitamins and others) and methods of administration (tablets, injections, droppers). The article discusses droppers for osteochondrosis: their difference from other forms of medication, some nuances and an overview of droppers by group.

Why all this complexity? Why can't you just get an injection? The fact is that droppers have some advantages that conventional injections cannot boast of:

  • The medicine enters the body continuously. This means that the effect of the treatment will last as long as the patient is on a drip.
  • It is very easy to maintain the desired dosage. Firstly, due to continuous receipt. Secondly, due to the fact that the medicine goes directly into the bloodstream, and not into the muscles. With injections, the final amount of medicine entering the body depends on many uncontrollable factors.
  • The human factor is excluded. When a doctor prescribes injections to a patient at home, the patient may simply forget to take the injection. The dropper solves this problem.

If in a particular case one or more of these benefits are very important, the doctor will prescribe an IV rather than injections.

Droppers can be simple or complex.

What distinguishes them from each other is their composition. The simple type of intravenous injection is a mixture of a vehicle (Ringer's solution, saline, or glucose) and a drug. Complex type droppers include several medications at once, which is necessary to achieve a certain effect.

Analgesics

Analgesics are medications that reduce or eliminate pain.

Decongestants

Sometimes, along with inflammation, edema occurs - an accumulation of fluid in the tissues. Edema worsens the course of the disease.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are needed to relieve inflammation that usually puts pressure on the nerve, leading to pain.

Muscle relaxants

This group of products relieves muscle spasms.

Sedatives

Sedatives are used to calm a weakened nervous system. Problems with it can arise both due to pain and stress, and due to a pinched cervical artery.

Other

All the droppers discussed above had a base and one drug necessary for treatment. But in some acute cases, when you need to quickly relieve dangerous or too strong symptoms, medication alone is not enough. When such a problem needs to be solved, doctors use complex IVs.

It should be noted that the final composition of a complex dropper largely depends on which medications the patient needs most and which of them are available right now.

The use of droppers for the treatment of osteochondrosis has its tangible advantages: direct delivery, controlled dose, reliability. In addition, droppers are indispensable if you need to stop an acute attack of the disease. The only drawback: the IV can only be placed in a hospital setting, so the patient must go to the hospital to receive it.

How to treat osteochondrosis? One of the degenerative changes in the articular surfaces of the spine is called osteochondrosis. Treatment of the disease continues for a long time and requires an integrated approach, including therapeutic treatment. The goals of therapy for osteochondrosis are aimed at relieving the causes and symptoms of the pathology, as well as suppressing degenerative changes.

  • analgesics;
  • non-steroidal anti-inflammatory drugs;
  • agents that restore cartilage tissue;
  • antispasmodic drugs;
  • vasodilators;
  • restoring abnormalities in blood circulation;
  • special means for normalizing metabolism in cartilage tissue;
  • immunomodulators.

Droppers are used to administer many of the drugs on the list.

The dropper is a transparent plastic tube with two metal needles at the ends: one is for insertion into the patient’s vein, the second is inserted into the container with the medicine. There is an extension in the middle of the tube to allow the infusion solution to accumulate. A device is attached to the tube to regulate the flow of the solution, which is used by a medical professional to change the rate at which the medicine enters the patient's body.

The container with the medicine must be placed above the patient's vein, so the bottle is mounted on a stand. A second needle is inserted into the container with the medicine to introduce air, displacing the solution from the bottle into the tube.

Actovegin

Actovegin is administered twice a day. It is recommended to administer 2 ml of medication per minute. To avoid complications, before the infusion procedure, the drug is checked for individual intolerance. Not used for IVs with pulmonary edema, insufficient heart function, swelling, insufficient or complete absence of urine accumulation in the bladder.

Vinpocetine

During infusion, the frequency of drops per minute should not exceed 80. In the first days of illness, dilute 2 ml per bottle of solution, in subsequent days the dose is increased to 5 ml. The course is continued for 2 weeks.

Trental

The severity of the disease allows you to use Trental without interruption during the day. For a person weighing 70 kg, Trental can be used in a dosage of 1 g per day, but not more than 1.2 g. The maximum volume of the infusion solution is up to 1.5 liters.

Contraindications for installing droppers with medication are bleeding, hemophilia, hemorrhagic stroke, pregnancy, subconjunctival hemorrhage.

Practice! Patients with coronary heart disease such as atrial fibrillation, hypertension, atherosclerosis of the blood vessels of the brain and heart should be observed during IV drips and, if their health worsens, immediately stop the infusion.

Eufillin

The drug is not indicated for infusion if insufficient functioning of the lungs, heart, kidneys, hemophilia, thyrotoxic conditions of hyperthyroidism, abnormalities in blood pressure are detected.

Neurological complications of lumbar osteochondrosis are an important medical, social and economic problem. A large number of people of working age are forced to spend a lot of time and money annually on stopping and preventing complications of this disease. In this regard, the relevance of the problem of choosing rational therapy for neurological manifestations of osteochondrosis is clear.

As is known, this treatment is complex and includes both the prescription of medications (pharmacotherapy) and the use of non-drug therapy methods, as well as surgical treatment. Let us dwell in more detail on the possibilities of pharmacotherapy. Its main directions in the treatment of neurological complications of lumbar osteochondrosis are the effect on pain, the muscular-tonic component, improving microcirculation and tissue trophism.

If acute pain occurs due to neurological complications of lumbar osteochondrosis, the patient should remain in bed for several days to reduce the volume and severity of movements in the affected area. The patient should take a comfortable, relaxed position on his back.

Often patients independently choose a position with a slightly raised back and slightly bent knees. The main requirement is that the patient lies on a hard surface in a position that is comfortable for him. Cold or light dry heat can relieve pain, while deep or strong heat often worsens it.

If there are signs of instability of the spinal motion segment and a tendency for pain to recur, it is advisable to wear a corset for several days. However, it should be remembered that wearing a corset for a long time can lead to weakening of the muscles. After complete relief of pain and elimination of discomfort, it is necessary to begin special exercise therapy classes with teaching the patient the correct movements without increasing the load on the spine, strengthening the muscles of the back and neck. As a rule, a course (7-10 procedures) of a qualified massage and swimming in warm water have a positive effect.

Modern technologies for administering anesthesia

The pain of the anesthesia itself, as well as its effectiveness, depend 90% on the skill of the dentist. A professional doctor will make every effort and use various techniques to make the patient feel comfortable. However, all people are different, each has their own pain threshold, and that is why an individual approach not only to the concentration of drugs, but also to premedication before the direct administration of anesthesia is very important.

Today, special anesthesia devices have been developed to help doctors. Naturally, they work under the supervision of a specialist. The electronic system is equipped with special pressure sensors - to avoid pain, the anesthetic must be injected very slowly and immediately after puncturing the tissue. The device is equipped with special needles with a very thin double tip, which again reduces pain.

In addition, by administering a small dose of anesthetic, a kind of allergy test is performed - the doctor assesses the condition of the soft mucous membranes (swelling, redness, rash) and the patient’s general reaction, and the pressure force is controlled by the device.

Safe, painless and effective treatment without pain! Treatment is carried out under the supervision of anesthesiologists capable of providing first aid. Special equipment monitors indicators of the general condition of the body.

If there is any threat, the ambulance station is 800 meters from the clinics! You are under the reliable protection of professionals.

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Infiltration anesthesia

Classic “freezing”, which is used in dentistry for almost any manipulation. The drug is injected under the mucosa, into the periosteum or directly into the bone. Depending on the procedure and the patient’s pain threshold, the required dosage is selected - for example, in case of acute pulpitis or complex tooth extraction, a higher concentration of the drug is used. If the patient is afraid of injections, topical anesthesia can additionally be used to numb the site of needle insertion, or xenon sedation.

When performing the procedure, the doctor must take into account the anatomy of the jaw system. For example, in the lower jaw the alveolar bone is denser, so anesthesia is less effective. In the upper jaw, when performing manipulations in the area of ​​wisdom teeth, there is a risk of the needle touching one of the branches of the facial nerve, which is fraught with the development of neuralgia. The clinic’s doctors have the necessary qualifications, so even the most complex anesthesia is performed completely safely for the patient.

What is local anesthesia?

Local anesthesia allows you to numb the specific area where the intervention is planned. The patient is conscious. And this is actually more than enough even for complex surgical operations.

For local administration of all types of anesthetics, special reusable syringes are used, which have a recess for inserting a carpule - this is a hermetically sealed ampoule with an anesthetic. Unlike disposable ones, carpule syringes have a thinner needle, which allows you to administer the drug slowly and thus eliminate pain. All syringes for reusable use must undergo antiseptic treatment and sterilization using modern ultrasonic and temperature sterilization equipment.

What is the drug mixture Boyko

Pain syndrome in various diseases of the musculoskeletal system and neurological pathologies can be so severe that it is impossible to get rid of it with conventional analgesics.

In this case, specialists use Boyko’s mixture, which contains drugs that can significantly reduce pain and improve the patient’s condition for several hours.

The popularity of this therapeutic cocktail lies in the effectiveness and availability of its components.

What it is

Boyko's mixture is a fast-acting and effective medicinal composition, widely used to relieve severe pain.

This is a multicomponent drug, which contains agents used to relieve pain, relieve inflammation and sedation.

The quantitative composition and proportion of components are not constant and can be changed by the decision of the attending physician depending on the patient’s condition. It is also acceptable to replace components due to individual intolerance.

Boyko's mixture does not eliminate the cause of severe pain, but only temporarily relieves it. It is very important, simultaneously with symptomatic therapy, to implement measures aimed at curing a person from the pathology that causes the development of pain. Only a specialist can make an accurate diagnosis.

Pharmacological properties

The mixture has a pronounced analgesic effect. The drug helps relax smooth muscles and relieve inflammatory processes in tissues.

Diphenhydramine, which is included in the composition, has a calming and sedative effect, which plays an important role in the treatment of severe pain that prevents the patient from falling asleep. In combination with cyanocobalamin (which also has a calming effect), diphenhydramine reduces agitation, eliminates increased anxiety, and even helps fight depression.

Indications and contraindications for use

The pronounced analgesic and anti-inflammatory effects of the medicinal mixture explain its popularity in the treatment of a number of neurological pathologies. The use of the medicinal composition is recommended for the symptomatic treatment of such painful conditions:

  • degenerative and degenerative-deformative pathologies of the musculoskeletal system (osteochondrosis of any location, arthritis, arthrosis, scoliosis, intervertebral hernia and others);
  • radiculitis;
  • vertebrogenic pain syndromes - cervicalgia (in the neck), thoracalgia (in the chest), lumbodynia (chronic lower back pain), lumbar ischialgia (in the lower back, radiating to one or both legs);
  • pathologies of peripheral nerves (intercostal neuralgia);
  • neuropathy;
  • sciatica (inflammation or pinching of the sciatic nerve);
  • mononeuritis, plexitis;
  • post-traumatic pain shock.

The drug has several contraindications, the main of which are allergies or individual intolerance to one or another component of the mixture. In addition, Boyko’s mixture is contraindicated in the following cases:

  • patient age – under 18 or over 70 years;
  • pregnancy and lactation;
  • cardiovascular diseases, including a history of second and third degree blockades, atrial fibrillation, heart disease, including congenital, myocardial infarction and others;
  • hematological pathologies - leukemia, leukemia, severe forms of anemia, hypoglobulinemia (decreased concentration of globulins in the blood serum), blood clotting disorders, hemorrhagic hemostasiopathy;
  • diseases of the digestive system in the acute stage - stomach ulcers, duodenal ulcers, granulomatous enteritis, ulcerative colitis, diverticulosis and others;
  • some liver pathologies;
  • glaucoma;
  • epilepsy.

The compound should be used with caution in patients suffering from bronchial asthma and benign prostatic hyperplasia.

Features of application

Before first use, a sensitivity test to novocaine is required.

If it is impossible to determine sensitivity to novocaine and vitamin B12, it is permissible to use only a combination of analgin (2 ml) plus diphenhydramine (1 ml).

Reminder before introducing the mixture

Before using this complex drug, you should consult a doctor - neurologist, traumatologist, surgeon, orthopedist, vertebrologist.

Typically, therapy using the Boyko mixture is carried out in a hospital.

Self-injections with this multi-component product are permissible only if you have experience and certain knowledge, since, for example, an air bubble in the syringe or injection of the product not deep enough into the muscle can lead to negative consequences. If the injection is performed under the supervision of a doctor, the patient will promptly report a deterioration in health, and the medical staff will take appropriate measures.

It is strictly prohibited to administer the composition intravenously. Intravenous infusion is performed only by drip. All components of the drug are pre-diluted in 200-400 ml of saline solution. Droppers are carried out under the supervision of medical staff. The effect after an intravenous injection occurs very quickly - literally in a few minutes, and lasts five hours.

Scheme and duration of treatment

Boyko's mixture is used for emergency relief of pain or in cases where other drugs do not have a positive effect. The medicine lasts only 3-5 hours, so it is recommended to use it 4-5 times a day. The course of symptomatic therapy should not exceed 5 days due to the risk of developing negative consequences.

Side effects

When using the mixture, the following adverse reactions are observed:

  • pain and tightness in the chest;
  • arrhythmia;
  • tachycardia;
  • trembling of limbs;
  • feeling dizzy;
  • weakness and apathy;
  • drowsiness;
  • skin rashes and itching;
  • decreased concentration;
  • anemia;
  • anaphylaxis.

If any of the listed negative effects occur, you must stop therapy and consult a doctor. Due to the risk of developing anaphylactic shock, the use of the mixture is recommended under the supervision of a medical professional in an environment where, if necessary, resuscitation measures can be carried out.

Long-term use of the drug can cause complications such as bronchospasm, a sharp decrease or, conversely, an increase in blood pressure, dysfunction of the hematopoietic and urinary systems.

Drug interactions

The simultaneous use of Boyko's mixture with alcohol is unacceptable.

Using the mixture simultaneously with other non-narcotic painkillers may increase the toxic effects of the latter.

Treatment with the mixture while taking contraceptives and tricyclic antidepressants disrupts metabolic reactions in the liver.

Simultaneous use with barbiturates reduces the analgesic effect of the mixture.

Use with Thiamazole and Sarcolysin leads to the development of leukopenia.

Boyko's mixture enhances the effect of muscle relaxants.

When used simultaneously with anticoagulants (heparin, warfarin), the risk of bleeding increases.

Other treatments

If a person has previously had a negative reaction to at least one of the components of the mixture, a combination of other drugs is possible. The most commonly used mixture is dexamethasone.

A few words about the popular variation of Boyko’s mixture with Dexamethasone - its composition and application. This remedy includes dexamethasone, lidocaine and sodium chloride solution, the amount of which is calculated by the doctor individually. The use of this compound is identical to the classical one, but the number of contraindications and side effects is much wider.

According to patient reviews, Boyko’s mixture provides quick but short-term relief from pain. Due to the fact that the drug cannot be used for a long time, you should consult your doctor for additional recommendations.

Source: https://oVakcine.ru/preparaty/chto-soboj-predstavlyaet-preparat-smes-bojko

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