Instructions for use of HILART FORTE

The liver is the second organ after the brain that does not have nerve endings, and therefore does not generate pain in our body. Why then do we say: “My liver hurts or aches.” Similar sensations that occur in the right hypochondrium occur when the liver becomes inflamed or exposed to various kinds of diseases. Increasing in size or deforming, the capsule stretches, and the liver begins to put pressure on adjacent organs and tissues, causing discomfort. Even the slightest discomfort in this area, which lasts more than one or two days, is a reason to pay close attention to the gland and get help.

In this article we talk about Essentiale, a drug for the treatment and prevention of liver diseases. When, how and why to use it, when the effect occurs.

Liver diseases

The liver is a very powerful and the only filter of our body. Nature made sure that this filter is capable of self-healing, because it carries vital functions:

  • Protective, or detoxifying, function of the liver. Some substances, such as barbiturates or alcohol, are completely destroyed in the liver. However, taking large doses of sleeping pills leads to damage to liver cells.
  • Removing harmful substances from the body.
  • Urea is formed in liver cells from ammonia. Urea from the liver travels through the bloodstream to the kidneys, from where it is excreted in the urine.
  • Formation and production of bile. Bile promotes the absorption of fats in the small intestine and the neutralization of hydrochloric acid.
  • The liver plays an important role in maintaining a constant blood composition.
  • Accumulation of nutrients, vitamins and iron.

The liver clears the blood of bilirubin, the remnants of red blood cells that have outlived their 110-day life. The gland is most active from 1 to 3 am. The fact that she is not all right is indicated by such symptoms as: dry throat, bitterness in the mouth, pain in the right hypochondrium, inability to bend over, heaviness, dull or aching sensations, increased bloating, constant nausea, vomiting, lightening of the stool, change in its consistency, darkening of urine, change in skin color (yellowishness of the skin and sclera), the appearance of “red spider veins,” weight loss, enlargement of internal organs, determined by palpation.

Causes of liver disease

Viruses and bacteria. Viral diseases include hepatitis types A, B, C, D and others. They provoke acute and chronic inflammatory processes. In 57% of cases, hepatitis develops into cirrhosis of the liver. The causes of bacterial infections are usually echinococcus, alveococcus and roundworms, as well as leptospira - the causative agents of leptospirosis. The diseases also occur in acute or chronic form and in the form of cystic transformation of the liver.

Violation of fat metabolism. In this case, the content of lipids (fats) in the liver cells increases, which is why the iron may increase in size and lose its ability to function normally. This leads to the development of diseases such as fatty hepatosis (steatosis of the liver) and subsequently to cirrhosis. Disorders of fat metabolism in the liver in Russia affect about 27% of the population.

Alcohol abuse. Systematic excessive consumption of alcoholic beverages has a detrimental effect on liver cells, which over time can cause cirrhosis. Researchers have derived a relatively safe daily dose of ethanol-containing drinks: less than 30 ml of vodka (cognac, whiskey), 150 ml of wine or 250 ml of beer per day for women and 60 ml of vodka (cognac, whiskey), 300 ml of wine or 500 ml of beer per day - for men.

Toxic damage from drugs. Occurs as a result of uncontrolled use of medications, which leads to changes in liver tissue and disruption of its normal functioning. There are acute and chronic forms of toxic lesions. Chronic diseases arise due to the constant ingestion of doses of toxic substances into the body. They can be asymptomatic for years.

When metabolic processes in the liver and gallbladder are disrupted, stones can form. These gallstones do not cause any discomfort for the time being. But one day the disease may manifest itself in the form of “biliary colic,” when severe pain occurs due to a stone getting stuck in the bile duct. This condition can be life-threatening.

Treatment of joints with Gilart: fast, safe, affordable!

In the drug "Gilart" the main active ingredient is sodium hyaluronate - an important component of connective tissue, which is present in high concentrations in the synovial fluid, dermis, vitreous body and umbilical cord.

The drug "Gilart-Forte" is a bioprosthesis of cartilage synovial fluid, which improves its viscoelastic properties.

Gilart-forte contains two active substances :

  • Sodium hyaluronate (sodium salt of hyaluronic acid).
  • Chondroitin sulfate.

These are high-quality and safe drugs (sterile and non-pyrogenic).

Hyaluronic acid is the main component of synovial fluid and, due to its specific properties, is responsible for lubrication and shock absorption in joints. These components reduce friction between joint surfaces and protect soft tissues from injury by acting as a shock absorber. Since the molecular weight of sodium hyaluronate is small, it is well absorbed into the tissue, resulting in an excellent therapeutic effect.

Hyaluronic acid also has:

  • painkiller,
  • anti-inflammatory,
  • antioxidant,
  • chondroprotective effect,
  • stimulates the synthesis of proteoglycans.

The quantity and quality of hyaluronic acid in synovial fluid is reduced in patients with osteoarthritis due to impaired synthesis by synovial and cartilage cells. As a result, the protection of the joint surface is significantly compromised, leaving the cartilage vulnerable to structural damage due to frictional and compressive forces.

Chondroitin sulfate is a structural analogue of cartilage tissue. It has anti-inflammatory and anti-catabolic effects, stimulates chondrocytes and the synthesis of proteoglycans, activates the synthesis of hyaluronic acid, suppresses the premature death of chondrocytes, normalizes bone structures, enhances the repair of hyaline cartilage and joint mobility.

Indications for use

The use of medications is indicated if degenerative disorders are detected in the joint. They are used in the treatment of:

  • osteoarthritis (osteoarthritis);
  • rheumatoid arthritis;
  • bursitis;
  • gout;
  • injuries that caused disruption of the joint structure;
  • deterioration of joint mobility.

Gilart is used to improve the visco-elastic properties of synovial fluid in the treatment of osteoarthrosis (osteoarthritis): gonarthrosis, coxarthrosis, osteoarthrosis of the carpometacarpal and temporomandibular joint; secondary post-traumatic osteoarthritis of large and medium joints; osteoarthritis due to orthopedic anomalies.

Gilart forte is shown:

  • for pronounced pain relief and prevention of complications after arthroscopy;
  • to increase joint mobility;
  • persons suffering from erosive intestinal lesions, peptic ulcers and undergoing treatment with glucocorticoids.

These effects persist for more than 6 months after one course of treatment.

Nobody likes local injections, especially into a joint that already hurts.

Composition of Essentiale

Essentiale is a complex of phospholipids from soybeans and choline (so-called essential phospholipids). Phospholipids are structural components of cell membranes. Contained in nervous tissue, they are involved in the delivery of fats, fatty acids and cholesterol. Any liver disease is, first of all, damage to the membranes of liver cells and their organelles, which leads to disturbances in the activity of enzymes and receptors associated with them, deterioration in the work and activity of liver cells and a decrease in the ability to regenerate.

Solution 1 ampoule, 5 ml
Active ingredient: phosphatidylcholine from soybean dried substance containing 93% (3-sn-phosphatidyl) choline: synonyms - “essential phospholipids”, “EPL®” - 250 mg.
Excipients: benzyl alcohol - 45 mg, deoxycholic acid -115 mg, sodium chloride - 12 mg, sodium hydroxide - 11.5 mg, riboflavin - 0.5 mg, ? – tocopherol – 0.75 mg, ethanol – 16.304 mg, water for injection – 4543, 680 mg.

Release form and dosage

The drug Essentiale is available in gelatin capsules and as an injection solution. The number of capsules per package can be 30, 90 and 180 pieces, ampoules per package - 5.

Indications for Essentiale

  • chronic hepatitis; cirrhosis of the liver; fatty liver of various etiologies; toxic liver damage; alcoholic hepatitis; liver dysfunction in other somatic diseases;
  • toxicosis of pregnancy;
  • prevention of recurrence of gallstone formation;
  • psoriasis (as an adjuvant therapy);
  • radiation syndrome.

Treatment regimens

Take capsules orally with plenty of water.

The drug is suitable for use in adolescents over 12 years of age and adults. The recommended dosage is 2 capsules. 3 times a day with meals.

There are no restrictions on the duration of treatment from the manufacturer, but depending on the severity of the disease, it is important to consult with a specialist. Maintenance therapy on a regular basis is possible only if there are clear signs of improvement. In other cases, the advisability of taking the medicine or replacing it is determined by a specialist.

According to consumer reviews, a positive effect occurs in a short time (for mild ailments); for severe or complex forms of the disease, in order to achieve a lasting effect, you need to drink a minimum course of a month. Perhaps as part of complex therapy.

Contraindications

One of the main contraindications is a tendency to allergic reactions. The fact is that Essentiale capsules contain soybean oil in the shell, which can provoke severe allergic reactions in people prone to such. Otherwise, the drug is well tolerated, with the exception of individual reactions of the body to the components of the composition.

Special Recommendations

Essentiale and alcohol

Since alcohol has a well-known toxic effect on the body and liver cells, the use of Essentiale and alcohol intake become incompatible concepts. In addition, one should not assume that the drug is capable of providing a supportive and protective effect on the liver while taking alcohol-containing products. During treatment with Essentiale, it is recommended to refrain from drinking alcohol.

Essentiale and diet

Compliance with a strictly mandatory diet during the course of Essentiale is not a strict obligation, but only a recommendation. Any disease of the digestive organs and glands requires dietary nutrition. Because diet is the basis for a positive outcome in such diseases. During the acute period of the disease, the liver is especially vulnerable and it needs support “on all fronts.” So, you should maximally exclude from the diet foods that load the liver and disrupt the motility of the biliary tract: fatty and fried foods, exclude smoked and pickled foods, any dough and fresh baked goods, baked goods (for example, dried bread, crackers and biscuits in reasonable quantities), strong, rich soups with mushroom, fish or meat broths, offal, foods cooked on the grill or fire, canned food, legumes, spices.

Essentiale during pregnancy

The drug Essentiale is recommended during pregnancy as a means of relieving toxicosis and nausea syndromes. However, during this period it should be taken strictly on the recommendation of a specialist, excluding potential risks for both the fetus and the expectant mother. But during breastfeeding, this drug is contraindicated, since research in this area has not been conducted.

Instructions for use of HILART FORTE

Medical product.

Has a pronounced analgesic effect.

Increases joint mobility in case of degenerative-dystrophic or traumatic damage to the knee and other synovial joints.

It is a bioprosthesis of synovial fluid, which improves its visco-elastic (viscosupplementary) properties. Hyaluronic acid is a major component of synovial fluid and cartilage and, due to its viscoelastic and rheological properties, is responsible for lubrication and shock absorption in joints. This reduces friction between joint surfaces and protects soft tissue from injury by acting as a shock absorber. Hyaluronic acid also has analgesic, anti-inflammatory, antioxidant and chondroprotective effects and stimulates the synthesis of proteoglycans. The quantity and quality of hyaluronic acid in synovial fluid is reduced in patients with osteoarthritis, as its synthesis by synovial cells and cartilage cells is impaired. Thus, the protection of the joint surfaces is greatly altered and the cartilage becomes vulnerable and subject to structural damage due to frictional and compressive forces.

Contains chondroitin sulfate, which is a structural analogue of cartilage tissue. The biological effects of chondroitin sulfate are extremely diverse, and it is a necessary component for the normal functioning of hyaline cartilage. Convincing evidence has been obtained that chondroitin sulfate has an anti-inflammatory effect, which is realized by inhibiting the activity of lysosomal enzymes, superoxide radicals and the expression of pro-inflammatory cytokines. In addition, it stimulates chondrocytes and the synthesis of proteoglycans with a normal polymer structure, and its anti-catabolic effect is due to the inhibition of metalloproteinases - stromelysin, collagenase, phospholipase A2. Activation of the synthesis of hyaluronic acid, suppression of premature death (apoptosis) of chondrocytes, and normalization of the structure of subchondral bone are also important. The effect of chondroitin sulfate in intensifying the repair of hyaline cartilage has been proven.

Thus, Gilart forte has a chondroprotective effect, relieves joint pain, improves joint mobility and protects cartilage.

Gilart forte is intended to restore the viscosity of synovial fluid. This therapy is safe, effective and well-established in the treatment of osteoarthritis and consists of injecting a hyaluronic acid-based solution into the affected synovial joint.

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